Philippe Froguel

Froguel in 2019 Philippe Froguel (born 14 April 1958) is a French physician and scientist who serves as chair in Genomic Medicine in the Department of Metabolism, Digestion and Reproduction at Imperial College London. His research has focused on the genetics of human diseases such as obesity and type 2 diabetes. This includes research identifying the genes glucokinase and HNF1 risk factors for type 2 diabetes. In 2007, he was elected to the Academy of Medical Sciences (UK). In 2017, he was elected corresponding member of the French Académie Nationale de Médecine, and he is also a member of the Mexican National Academy of Medicine (Academia Nacional de Medicina de México).

Froguel received his M.D. from Pierre and Marie Curie University and his Ph.D. from Paris Diderot University. Provided by Wikipedia
Showing 1 - 10 results of 10 for search 'Philippe Froguel', query time: 0.07s Refine Results
  1. 1
    Inflammatory Role of Toll-Like Receptors in Human and Murine Adipose Tissue

    Inflammatory Role of Toll-Like Receptors in Human and Murine Adipose Tissue by Odile Poulain-Godefroy, Olivier Le Bacquer, Pauline Plancq, Cécile Lecœur, François Pattou, Gema Frühbeck, Philippe Froguel

    Published 2010
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  2. 2
    Impact of statistical models on the prediction of type 2 diabetes using non-targeted metabolomics profiling

    Impact of statistical models on the prediction of type 2 diabetes using non-targeted metabolomics profiling by Loic Yengo, Abdelilah Arredouani, Michel Marre, Ronan Roussel, Martine Vaxillaire, Mario Falchi, Abdelali Haoudi, Jean Tichet, Beverley Balkau, Amélie Bonnefond, Philippe Froguel

    Published 2016
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  3. 3
    A de novo synonymous variant in EFTUD2 disrupts normal splicing and causes mandibulofacial dysostosis with microcephaly: case report

    A de novo synonymous variant in EFTUD2 disrupts normal splicing and causes mandibulofacial dysostosis with microcephaly: case report by Arthur Jacob, Jennifer Pasquier, Raphael Carapito, Frédéric Auradé, Anne Molitor, Philippe Froguel, Khalid Fakhro, Najeeb Halabi, Géraldine Viot, Seiamak Bahram, Arash Rafii

    Published 2020
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  4. 4
    Impaired histone deacetylases 5 and 6 expression mimics the effects of obesity and hypoxia on adipocyte function

    Impaired histone deacetylases 5 and 6 expression mimics the effects of obesity and hypoxia on adipocyte function by Julien Bricambert, Dimitri Favre, Saška Brajkovic, Amélie Bonnefond, Raphael Boutry, Roberto Salvi, Valérie Plaisance, Mohamed Chikri, Giulia Chinetti-Gbaguidi, Bart Staels, Vittorio Giusti, Robert Caiazzo, François Pattou, Gérard Waeber, Philippe Froguel, Amar Abderrahmani

    Published 2016
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  5. 5
    Cdkn2a deficiency promotes adipose tissue browning

    Cdkn2a deficiency promotes adipose tissue browning by Nabil Rabhi, Sarah Anissa Hannou, Xavier Gromada, Elisabet Salas, Xi Yao, Frédérik Oger, Charlène Carney, Isabel C. Lopez-Mejia, Emmanuelle Durand, Iandry Rabearivelo, Amélie Bonnefond, Emilie Caron, Lluis Fajas, Christian Dani, Philippe Froguel, Jean-Sébastien Annicotte

    Published 2018
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  6. 6
    Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2 diabetes

    Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2 diabetes by Amna Khamis, Mickaël Canouil, Afshan Siddiq, Hutokshi Crouch, Mario Falchi, Manon von Bulow, Florian Ehehalt, Lorella Marselli, Marius Distler, Daniela Richter, Jürgen Weitz, Krister Bokvist, Ioannis Xenarios, Bernard Thorens, Anke M. Schulte, Mark Ibberson, Amelie Bonnefond, Piero Marchetti, Michele Solimena, Philippe Froguel

    Published 2019
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  7. 7
    Exploring the role of purinergic receptor P2RY1 in type 2 diabetes risk and pathophysiology: Insights from human functional genomics

    Exploring the role of purinergic receptor P2RY1 in type 2 diabetes risk and pathophysiology: Insights from human functional genomics by Arnaud Dance, Justine Fernandes, Bénédicte Toussaint, Emmanuel Vaillant, Raphaël Boutry, Morgane Baron, Hélène Loiselle, Beverley Balkau, Guillaume Charpentier, Sylvia Franc, Mark Ibberson, Michel Marre, Marie Gernay, Marjorie Fadeur, Nicolas Paquot, Martine Vaxillaire, Mathilde Boissel, Souhila Amanzougarene, Mehdi Derhourhi, Amna Khamis, Philippe Froguel, Amélie Bonnefond

    Published 2024
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  8. 8
    Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion

    Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion by Fatou K. Ndiaye, Ana Ortalli, Mickaël Canouil, Marlène Huyvaert, Clara Salazar-Cardozo, Cécile Lecoeur, Marie Verbanck, Valérie Pawlowski, Raphaël Boutry, Emmanuelle Durand, Iandry Rabearivelo, Olivier Sand, Lorella Marselli, Julie Kerr-Conte, Vikash Chandra, Raphaël Scharfmann, Odile Poulain-Godefroy, Piero Marchetti, François Pattou, Amar Abderrahmani, Philippe Froguel, Amélie Bonnefond

    Published 2017
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  9. 9
    CoDE-seq, an augmented whole-exome sequencing, enables the accurate detection of CNVs and mutations in Mendelian obesity and intellectual disability

    CoDE-seq, an augmented whole-exome sequencing, enables the accurate detection of CNVs and mutations in Mendelian obesity and intellectual disability by Louise Montagne, Mehdi Derhourhi, Amélie Piton, Bénédicte Toussaint, Emmanuelle Durand, Emmanuel Vaillant, Dorothée Thuillier, Stefan Gaget, Franck De Graeve, Iandry Rabearivelo, Amélie Lansiaux, Bruno Lenne, Sylvie Sukno, Rachel Desailloud, Miriam Cnop, Ramona Nicolescu, Lior Cohen, Jean-François Zagury, Mélanie Amouyal, Jacques Weill, Jean Muller, Olivier Sand, Bruno Delobel, Philippe Froguel, Amélie Bonnefond

    Published 2018
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  10. 10
    Meta‐analysis of genome‐wide DNA methylation and integrative omics of age in human skeletal muscle

    Meta‐analysis of genome‐wide DNA methylation and integrative omics of age in human skeletal muscle by Sarah Voisin, Macsue Jacques, Shanie Landen, Nicholas R. Harvey, Larisa M. Haupt, Lyn R. Griffiths, Sofiya Gancheva, Meriem Ouni, Markus Jähnert, Kevin J. Ashton, Vernon G. Coffey, Jamie‐Lee M. Thompson, Thomas M. Doering, Anne Gabory, Claudine Junien, Robert Caiazzo, Hélène Verkindt, Violetta Raverdy, François Pattou, Philippe Froguel, Jeffrey M. Craig, Sara Blocquiaux, Martine Thomis, Adam P. Sharples, Annette Schürmann, Michael Roden, Steve Horvath, Nir Eynon

    Published 2021
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