Resultados da pesquisa - Xiaoguang Chen

A Novel PARP Inhibitor YHP-836 For the Treatment of BRCA-Deficiency Cancers Por Tingting Du, Zhihui Zhang, Jie Zhou, Li Sheng, Haiping Yao, Ming Ji, Bailing Xu, Xiaoguang Chen, Xiaoguang Chen

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Long non-coding RNAs: From disease code to drug role Por Yuanyuan Chen, Zhaojun Li, Xiaoguang Chen, Sen Zhang

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The PI3K Inhibitor XH30 Enhances Response to Temozolomide in Drug-Resistant Glioblastoma via the Noncanonical Hedgehog Signaling Pathway Por Ming Ji, Ming Ji, Zhihui Zhang, Songwen Lin, Chunyang Wang, Jing Jin, Jing Jin, Nina Xue, Heng Xu, Xiaoguang Chen, Xiaoguang Chen

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A Dual PI3K/HDAC Inhibitor Downregulates Oncogenic Pathways in Hematologic Tumors In Vitro and In Vivo Por Zheng Yan, Kehui Zhang, Ming Ji, Heng Xu, Xiaoguang Chen

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Sphingosine-1-Phosphate Receptor Subtype 1 (S1P1) Modulator IMMH001 Regulates Adjuvant- and Collagen-Induced Arthritis Por Jing Jin, Ming Ji, Rong Fu, Mingjin Wang, Nina Xue, Qiong Xiao, Jingpin Hu, Xiaojian Wang, Fangfang Lai, Dali Yin, Xiaoguang Chen, Xiaoguang Chen

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Strongyloidiasis--an insight into its global prevalence and management. Por Santhosh Puthiyakunnon, Swapna Boddu, Yiji Li, Xiaohong Zhou, Chunmei Wang, Juan Li, Xiaoguang Chen

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Chlorogenic Acid Relieves the Lupus Erythematosus-like Skin Lesions and Arthritis in MRL/lpr Mice Por Ruxuan Wang, Xiaoyi Yang, Shen You, Mengyao Hao, Jianguang Li, Xiaoguang Chen, Jing Jin

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Total Coumarins from Hydrangea paniculata Show Renal Protective Effects in Lipopolysaccharide-Induced Acute Kidney Injury via Anti-inflammatory and Antioxidant Activities Por Sen Zhang, Jie Ma, Li Sheng, Dongming Zhang, Xiaoguang Chen, Jingzhi Yang, Dongjie Wang

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Assessing the risk of spread of Zika virus under current and future climate scenarios Por Ye Xu, Jingni Zhou, Tong Liu, Peiwen Liu, Yang Wu, Zetian Lai, Jinbao Gu, Xiaoguang Chen

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Dynamic gut microbiome-metabolome in cationic bovine serum albumin induced experimental immune-complex glomerulonephritis and effect of losartan and mycophenolate mofetil on microb... Por Wenying Shi, Zhaojun Li, Weida Wang, Xikun Liu, Haijie Wu, Xiaoguang Chen, Xunrong Zhou, Sen Zhang

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ACAT1 deficiency in myeloid cells promotes glioblastoma progression by enhancing the accumulation of myeloid-derived suppressor cells Por Mingjin Wang, Weida Wang, Shen You, Zhenyan Hou, Ming Ji, Nina Xue, Tingting Du, Xiaoguang Chen, Jing Jin

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Target fishing and mechanistic insights of the natural anticancer drug candidate chlorogenic acid Por Qinghua Wang, Tingting Du, Zhihui Zhang, Qingyang Zhang, Jie Zhang, Wenbin Li, Jian-Dong Jiang, Xiaoguang Chen, Hai-Yu Hu

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Author correction to "YPD-30, a prodrug of YPD-29B, is an oral small-molecule inhibitor targeting PD-L1 for the treatment of human cancer" [Acta Pharmaceutica Sinica B 12 (2022) 28... Por Fangfang Lai, Ming Ji, Lei Huang, Yunchen Wang, Nina Xue, Tingting Du, Kai Dong, Xiaoqing Yao, Jing Jin, Zhiqiang Feng, Xiaoguang Chen

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YPD-30, a prodrug of YPD-29B, is an oral small-molecule inhibitor targeting PD-L1 for the treatment of human cancer Por Fangfang Lai, Ming Ji, Lei Huang, Yunchen Wang, Nina Xue, Tingting Du, Kai Dong, Xiaoqing Yao, Jing Jin, Zhiqiang Feng, Xiaoguang Chen

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S-72, a Novel Orally Available Tubulin Inhibitor, Overcomes Paclitaxel Resistance via Inactivation of the STING Pathway in Breast Cancer Por Zhenyan Hou, Songwen Lin, Tingting Du, Mingjin Wang, Weida Wang, Shen You, Nina Xue, Yichen Liu, Ming Ji, Heng Xu, Xiaoguang Chen

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Metabolism and Interspecies Variation of IMMH-010, a Programmed Cell Death Ligand 1 Inhibitor Prodrug Por Yuchen Wang, Xiao Liu, Xiaowen Zou, Shuting Wang, Lijun Luo, Yuke Liu, Kai Dong, Xiaoqing Yao, Yan Li, Xiaoguang Chen, Li Sheng

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A novel PI3K inhibitor XH30 suppresses orthotopic glioblastoma and brain metastasis in mice models Por Ming Ji, Dongjie Wang, Songwen Lin, Chunyang Wang, Ling Li, Zhihui Zhang, Jing Jin, Deyu Wu, Yi Dong, Heng Xu, Duo Lu, Xiaoguang Chen

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Q63, a novel DENV2 RdRp non-nucleoside inhibitor, inhibited DENV2 replication and infection Por Xingang Yao, Songxin Guo, Wenyu Wu, Jinan Wang, Shengen Wu, Shijun He, Yihong Wan, Kutty Selva Nandakumar, Xiaoguang Chen, Ning Sun, Qiuhua Zhu, Shuwen Liu

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Extracellular vesicles in the HCC microenvironment: Implications for therapy and biomarkers Por Le Cheng, Limin Zhang, Xiaoxiao Wang, Yufei Wang, Jiahui Yu, Mengnan Li, Zhaowu Ma, Paul Chi-Lui Ho, Xiaoguang Chen, Lingzhi Wang, Gautam Sethi, Boon-Cher Goh

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A novel S1P1 modulator IMMH002 ameliorates psoriasis in multiple animal models Por Jing Jin, Nina Xue, Yuan Liu, Rong Fu, Mingjin Wang, Ming Ji, Fangfang Lai, Jinping Hu, Xiaojian Wang, Qiong Xiao, Xiaoying Zhang, Dali Yin, Liping Bai, Xiaoguang Chen, Shuan Rao

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