Хайлтын үр дүнгүүд - Joshua F Apgar

Mechanistic PK/PD modeling to address early-stage biotherapeutic dosing feasibility questions -н Joshuaine Grant, Fei Hua, Joshua F. Apgar, John M. Burke, Diana H. Marcantonio

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Quantitative systems pharmacology model of GITR‐mediated T cell dynamics in tumor microenvironment -н Yan Ji, Kumpal Madrasi, Deborah A. Knee, Lore Gruenbaum, Joshua F. Apgar, John M. Burke, Bruce Gomes

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Early Feasibility Assessment: A Method for Accurately Predicting Biotherapeutic Dosing to Inform Early Drug Discovery Decisions -н Diana H. Marcantonio, Andrew Matteson, Marc Presler, John M. Burke, David R. Hagen, Fei Hua, Joshua F. Apgar

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Quantitative Systems Pharmacology Model of a Masked, Tumor‐Activated Antibody -н Mark Stroh, Jason Sagert, John M. Burke, Joshua F. Apgar, Lin Lin, Bjorn L. Millard, W. Michael Kavanaugh

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Comparison of dose selection based on target engagement versus inhibition of receptor-ligand interaction for checkpoint inhibitors -н Sarah A. Head, Carter Johnson, Saheli Sarkar, Andrew Matteson, Diana H. Marcantonio, Fei Hua, John M. Burke, Joshua F. Apgar, David Flowers

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Virtual clinical trial simulations for a novel KRASG12C inhibitor (ASP2453) in non‐small cell lung cancer -н Hiroyuki Sayama, Diana Marcantonio, Takeyuki Nagashima, Masashi Shimazaki, Tsuyoshi Minematsu, Joshua F Apgar, John M. Burke, Lucia Wille, Yasuhisa Nagasaka, Daniel C. Kirouac

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Quantitative systems pharmacology model for Alzheimer's disease to predict the effect of aducanumab on brain amyloid -н Lin Lin, Fei Hua, Cristian Salinas, Carissa Young, Thierry Bussiere, Joshua F. Apgar, John M. Burke, Kumar Kandadi Muralidharan, Rajasimhan Rajagovindan, Ivan Nestorov

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A systems pharmacology model for gene therapy in sickle cell disease -н Bo Zheng, Lucia Wille, Karsten Peppel, David Hagen, Andrew Matteson, Jeffrey Ahlers, James Schaff, Fei Hua, Theresa Yuraszeck, Enoch Cobbina, Joshua F. Apgar, John M. Burke, John Roberts, Raibatak Das

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