Showing 1 - 14 results of 14 for search 'Pascal Girard', query time: 0.05s Refine Results
  1. 1
    Population pharmacokinetic and pharmacodynamic modeling of evobrutinib in healthy adult participants

    Population pharmacokinetic and pharmacodynamic modeling of evobrutinib in healthy adult participants by Orestis Papasouliotis, David Mitchell, Pascal Girard, Martin Dyroff

    Published 2022
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  2. 2
    Determination of a clinically effective evobrutinib dose: Exposure-response analyses of a phase II relapsing multiple sclerosis study

    Determination of a clinically effective evobrutinib dose: Exposure-response analyses of a phase II relapsing multiple sclerosis study by Orestis Papasouliotis, David Mitchell, Pascal Girard, Fernando Dangond, Martin Dyroff

    Published 2022
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  3. 3
    Assessing Similarity Among Individual Tumor Size Lesion Dynamics: The CICIL Methodology

    Assessing Similarity Among Individual Tumor Size Lesion Dynamics: The CICIL Methodology by Nadia Terranova, Pascal Girard, Konstantinos Ioannou, Ute Klinkhardt, Alain Munafo

    Published 2018
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  4. 4
    Semimechanistic Clearance Models of Oncology Biotherapeutics and Impact of Study Design: Cetuximab as a Case Study

    Semimechanistic Clearance Models of Oncology Biotherapeutics and Impact of Study Design: Cetuximab as a Case Study by Ana‐Marija Grisic, Akash Khandelwal, Mauro Bertolino, Wilhelm Huisinga, Pascal Girard, Charlotte Kloft

    Published 2020
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  5. 5
    Population pharmacokinetics of atacicept in systemic lupus erythematosus: An analysis of three clinical trials

    Population pharmacokinetics of atacicept in systemic lupus erythematosus: An analysis of three clinical trials by Maria Pitsiu, Özkan Yalkinoglu, Colm Farrell, Pascal Girard, Cristina Vazquez‐Mateo, Orestis Papasouliotis

    Published 2023
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  6. 6
    Predicting disease activity in patients with multiple sclerosis: An explainable machine‐learning approach in the Mavenclad trials

    Predicting disease activity in patients with multiple sclerosis: An explainable machine‐learning approach in the Mavenclad trials by Sreetama Basu, Alain Munafo, Ali‐Frederic Ben‐Amor, Sanjeev Roy, Pascal Girard, Nadia Terranova

    Published 2022
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  7. 7
    Designing phase I oncology dose escalation using dose-exposure-toxicity models as a complementary approach to model‐based dose-toxicity models

    Designing phase I oncology dose escalation using dose-exposure-toxicity models as a complementary approach to model‐based dose-toxicity models by Kristyn Pantoja, Shankar Lanke, Alain Munafo, Anja Victor, Christina Habermehl, Armin Schueler, Karthik Venkatakrishnan, Pascal Girard, Kosalaram Goteti

    Published 2022
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  8. 8
    Translational pharmacokinetic‐pharmacodynamic modeling of preclinical and clinical data of the oral MET inhibitor tepotinib to determine the recommended phase II dose

    Translational pharmacokinetic‐pharmacodynamic modeling of preclinical and clinical data of the oral MET inhibitor tepotinib to determine the recommended phase II dose by Wenyuan Xiong, Manja Friese‐Hamim, Andreas Johne, Christopher Stroh, Manfred Klevesath, Gerald S. Falchook, David S. Hong, Pascal Girard, Samer El Bawab

    Published 2021
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  9. 9
    Tumor growth inhibition modeling in patients with second line biliary tract cancer and first line non‐small cell lung cancer based on bintrafusp alfa trials

    Tumor growth inhibition modeling in patients with second line biliary tract cancer and first line non‐small cell lung cancer based on bintrafusp alfa trials by Ana‐Marija Milenković‐Grišić, Nadia Terranova, Diane R. Mould, Yulia Vugmeyster, Thomas Mrowiec, Andreas Machl, Pascal Girard, Karthik Venkatakrishnan, Akash Khandelwal

    Published 2024
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  10. 10
    Time‐Varying Clearance and Impact of Disease State on the Pharmacokinetics of Avelumab in Merkel Cell Carcinoma and Urothelial Carcinoma

    Time‐Varying Clearance and Impact of Disease State on the Pharmacokinetics of Avelumab in Merkel Cell Carcinoma and Urothelial Carcinoma by Justin J. Wilkins, Brigitte Brockhaus, Haiqing Dai, Yulia Vugmeyster, Joleen T. White, Satjit Brar, Carlo L. Bello, Berend Neuteboom, Janet R. Wade, Pascal Girard, Akash Khandelwal

    Published 2019
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  11. 11
    A multistate modeling and simulation framework to learn dose-response of oncology drugs: Application to bintrafusp alfa in non‐small cell lung cancer

    A multistate modeling and simulation framework to learn dose-response of oncology drugs: Application to bintrafusp alfa in non‐small cell lung cancer by Han Liu, Ana‐Marija Milenković‐Grišić, Sreenath M. Krishnan, Siv Jönsson, Lena E. Friberg, Pascal Girard, Karthik Venkatakrishnan, Yulia Vugmeyster, Akash Khandelwal, Mats O. Karlsson

    Published 2023
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  12. 12
    Pharmacometric modeling and machine learning analyses of prognostic and predictive factors in the JAVELIN Gastric 100 phase III trial of avelumab

    Pharmacometric modeling and machine learning analyses of prognostic and predictive factors in the JAVELIN Gastric 100 phase III trial of avelumab by Nadia Terranova, Jonathan French, Haiqing Dai, Matthew Wiens, Akash Khandelwal, Ana Ruiz‐Garcia, Juliane Manitz, Anja vonHeydebreck, Mary Ruisi, Kevin Chin, Pascal Girard, Karthik Venkatakrishnan

    Published 2022
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  13. 13
    Disease trajectory of SLE clinical endpoints and covariates affecting disease severity and probability of response: Analysis of pooled patient‐level placebo (Standard‐of‐Care) data to enable model‐informed drug development

    Disease trajectory of SLE clinical endpoints and covariates affecting disease severity and probability of response: Analysis of pooled patient‐level placebo (Standard‐of‐Care) data... by Kosalaram Goteti, Jonathan French, Ramon Garcia, Ying Li, Florence Casset‐Semanaz, Aida Aydemir, Robert Townsend, Cristina Vazquez Mateo, Matthew Studham, Oliver Guenther, Amy Kao, Marc Gastonguay, Pascal Girard, Lisa Benincosa, Karthik Venkatakrishnan

    Published 2023
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  14. 14
    Modeling tumor size dynamics based on real‐world electronic health records and image data in advanced melanoma patients receiving immunotherapy

    Modeling tumor size dynamics based on real‐world electronic health records and image data in advanced melanoma patients receiving immunotherapy by Perrine Courlet, Daniel Abler, Monia Guidi, Pascal Girard, Federico Amato, Naik Vietti Violi, Matthieu Dietz, Nicolas Guignard, Alexandre Wicky, Sofiya Latifyan, Rita De Micheli, Mario Jreige, Clarisse Dromain, Chantal Csajka, John O. Prior, Karthik Venkatakrishnan, Olivier Michielin, Michel A. Cuendet, Nadia Terranova

    Published 2023
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