Showing 1 - 9 results of 9 for search 'Saroja Ramanujan', query time: 0.08s Refine Results
  1. 1
    A Flexible Approach for Context‐Dependent Assessment of Quantitative Systems Pharmacology Models

    A Flexible Approach for Context‐Dependent Assessment of Quantitative Systems Pharmacology Models by Saroja Ramanujan, Jason R. Chan, Christina M. Friedrich, Craig J. Thalhauser

    Published 2019
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  2. 2
    gQSPSim: A SimBiology‐Based GUI for Standardized QSP Model Development and Application

    gQSPSim: A SimBiology‐Based GUI for Standardized QSP Model Development and Application by Iraj Hosseini, Justin Feigelman, Anita Gajjala, Monica Susilo, Vidya Ramakrishnan, Saroja Ramanujan, Kapil Gadkar

    Published 2020
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  3. 3
    Navigating Between Right, Wrong, and Relevant: The Use of Mathematical Modeling in Preclinical Decision Making

    Navigating Between Right, Wrong, and Relevant: The Use of Mathematical Modeling in Preclinical Decision Making by Anna Kondic, Dean Bottino, John Harrold, Jeffrey D. Kearns, CJ Musante, Aleksandrs Odinecs, Saroja Ramanujan, Jangir Selimkhanov, Birgit Schoeberl

    Published 2022
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  4. 4
    Quantitative systems pharmacology model‐based investigation of adverse gastrointestinal events associated with prolonged treatment with PI3‐kinase inhibitors

    Quantitative systems pharmacology model‐based investigation of adverse gastrointestinal events associated with prolonged treatment with PI3‐kinase inhibitors by Kapil Gadkar, Christina Friedrich, Vincent Hurez, Maria‐Luisa Ruiz, Leslie Dickmann, Mohit Kumar Jolly, Leah Schutt, Jin Jin, Joseph A. Ware, Saroja Ramanujan

    Published 2022
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  5. 5
    A mechanistic PK/PD model to enable dose selection of the potent anti‐tryptase antibody (MTPS9579A) in patients with moderate‐to‐severe asthma

    A mechanistic PK/PD model to enable dose selection of the potent anti‐tryptase antibody (MTPS9579A) in patients with moderate‐to‐severe asthma by Sharon M. Rymut, Lindsay M. Henderson, Victor Poon, Tracy L. Staton, Fang Cai, Siddharth Sukumaran, Horace Rhee, Ryan Owen, Saroja Ramanujan, Kenta Yoshida

    Published 2023
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  6. 6
    Systems‐based digital twins to help characterize clinical dose-response and propose predictive biomarkers in a Phase I study of bispecific antibody, mosunetuzumab, in NHL

    Systems‐based digital twins to help characterize clinical dose-response and propose predictive biomarkers in a Phase I study of bispecific antibody, mosunetuzumab, in NHL by Monica E. Susilo, Chi‐Chung Li, Kapil Gadkar, Genevive Hernandez, Ling‐Yuh Huw, Jin Y. Jin, Shen Yin, Michael C. Wei, Saroja Ramanujan, Iraj Hosseini

    Published 2023
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  7. 7
    Integrated systems modeling of severe asthma: Exploration of IL‐33/ST2 antagonism

    Integrated systems modeling of severe asthma: Exploration of IL‐33/ST2 antagonism by Kapil Gadkar, Justin Feigelman, Siddharth Sukumaran, Manoj C. Rodrigo, Tracy Staton, Fang Cai, Rebecca N. Bauer, David F. Choy, Cynthia L. Stokes, Heleen Scheerens, Saroja Ramanujan

    Published 2022
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  8. 8
    A Minimal PBPK/PD Model with Expansion-Enhanced Target-Mediated Drug Disposition to Support a First-in-Human Clinical Study Design for a FLT3L-Fc Molecule

    A Minimal PBPK/PD Model with Expansion-Enhanced Target-Mediated Drug Disposition to Support a First-in-Human Clinical Study Design for a FLT3L-Fc Molecule by Iraj Hosseini, Brett Fleisher, Jennifer Getz, Jérémie Decalf, Mandy Kwong, Meric Ovacik, Travis W. Bainbridge, Christine Moussion, Gautham K. Rao, Kapil Gadkar, Amrita V. Kamath, Saroja Ramanujan

    Published 2024
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  9. 9
    Quantitative systems pharmacology model of the amyloid pathway in Alzheimer's disease: Insights into the therapeutic mechanisms of clinical candidates

    Quantitative systems pharmacology model of the amyloid pathway in Alzheimer's disease: Insights into the therapeutic mechanisms of clinical candidates by Vidya Ramakrishnan, Christina Friedrich, Colleen Witt, Robert Sheehan, Meghan Pryor, Jasvinder K. Atwal, Kristin Wildsmith, Katherine Kudrycki, Seung‐Hye Lee, Norman Mazer, Carsten Hofmann, Reina N. Fuji, Jin Y. Jin, Saroja Ramanujan, Michael Dolton, Angelica Quartino

    Published 2023
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