Search Results - Erik de Clercq

An Odyssey in antiviral drug development-50 years at the Rega Institute: 1964-2014 by Erik De Clercq

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Milestones in the discovery of antiviral agents: nucleosides and nucleotides by Erik de Clercq

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Approved HIV reverse transcriptase inhibitors in the past decade by Guangdi Li, Yali Wang, Erik De Clercq

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Author correction to 'Approved HIV reverse transcriptase inhibitors in the past decade' [Acta Pharmaceutica Sinica B 12 (2022) 1567-1590] by Guangdi Li, Yali Wang, Erik De Clercq

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Development of non-nucleoside reverse transcriptase inhibitors (NNRTIs): our past twenty years by Chunlin Zhuang, Christophe Pannecouque, Erik De Clercq, Fener Chen

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Picomolar inhibitor of reverse transcriptase featuring significantly improved metabolic stability by Ya-Li Sang, Christophe Pannecouque, Erik De Clercq, Shuai Wang, Fen-Er Chen

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Structure-based design of novel heterocycle-substituted ATDP analogs as non-nucleoside reverse transcriptase inhibitors with improved selectivity and solubility by Li-Min Zhao, Christophe Pannecouque, Erik De Clercq, Shuai Wang, Fen-Er Chen

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Improving the positional adaptability: structure-based design of biphenyl-substituted diaryltriazines as novel non-nucleoside HIV-1 reverse transcriptase inhibitors by Kaijun Jin, Minjie Liu, Chunlin Zhuang, Erik De Clercq, Christophe Pannecouque, Ge Meng, Fener Chen

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Structure-based design and optimization lead to the identification of novel dihydrothiopyrano[3,2-d]pyrimidine derivatives as potent HIV-1 inhibitors against drug-resistant variant... by Zhao Wang, Heng Zhang, Zhen Gao, Zihao Sang, Erik De Clercq, Christophe Pannecouque, Dongwei Kang, Peng Zhan, Xinyong Liu

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Identification of Novel Diarylpyrimidines as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors by Exploring the Primer Grip Region by Tao Zhang, Zhongxia Zhou, Fabao Zhao, Zihao Sang, Erik De Clercq, Christophe Pannecouque, Dongwei Kang, Peng Zhan, Xinyong Liu

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Epidemiology and Clinical Outcomes of HIV Infection in South-Central China: A Retrospective Study From 2003 to 2018 by Tingting Yue, Pan Zhang, Yuantao Hao, Jianmei He, Jun Zheng, Erik De Clercq, Guangdi Li, Guangdi Li, Yaxiong Huang, Fang Zheng

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Development of fluorine-substituted NH2-biphenyl-diarylpyrimidines as highly potent non-nucleoside reverse transcriptase inhibitors: Boosting the safety and metabolic stability by Xin Jin, Shuai Wang, Limin Zhao, Wenjuan Huang, Yinxiang Zhang, Christophe Pannecouque, Erik De Clercq, Ge Meng, Huri Piao, Fener Chen

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Design and optimization of piperidine-substituted thiophene[3,2-d]pyrimidine-based HIV-1 NNRTIs with improved drug resistance and pharmacokinetic profiles by Yanying Sun, Zhenzhen Zhou, Zhongling Shi, Fabao Zhao, Minghui Xie, Zongji Zhuo, Erik De Clercq, Christophe Pannecouque, Dongwei Kang, Peng Zhan, Xinyong Liu

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Gender disparity and temporal trend of liver cancer in China from 1990 to 2019 and predictions in a 25-year period by Tingting Yue, Ming Xu, Ting Cai, Haizhen Zhu, Mahmoud Reza Pourkarim, Mahmoud Reza Pourkarim, Mahmoud Reza Pourkarim, Erik De Clercq, Guangdi Li, Guangdi Li

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Exploring the hydrophobic channel of NNIBP leads to the discovery of novel piperidine-substituted thiophene[3,2-d]pyrimidine derivatives as potent HIV-1 NNRTIs by Dongwei Kang, Da Feng, Tiziana Ginex, Jinmi Zou, Fenju Wei, Tong Zhao, Boshi Huang, Yanying Sun, Samuel Desta, Erik De Clercq, Christophe Pannecouque, Peng Zhan, Xinyong Liu

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Discovery of novel sulfonamide substituted indolylarylsulfones as potent HIV-1 inhibitors with better safety profiles by Shenghua Gao, Letian Song, Yusen Cheng, Fabao Zhao, Dongwei Kang, Shu Song, Mianling Yang, Bing Ye, Wei Zhao, Yajie Tang, Erik De Clercq, Christophe Pannecouque, Peng Zhan, Xinyong Liu

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