Ohcanbohtosat - Jos H. Beijnen

Combining Isotopic Tracer Techniques to Increase Efficiency of Clinical Pharmacokinetic Trials in Oncology Dahkki Jeroen Roosendaal, Hilde Rosing, Jos H. Beijnen

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Drug Transporters ABCB1 (P-gp) and OATP, but not Drug-Metabolizing Enzyme CYP3A4, Affect the Pharmacokinetics of the Psychoactive Alkaloid Ibogaine and its Metabolites Dahkki Margarida L. F. Martins, Paniz Heydari, Paniz Heydari, Wenlong Li, Alejandra Martínez-Chávez, Alejandra Martínez-Chávez, Nikkie Venekamp, Maria C. Lebre, Luc Lucas, Jos H. Beijnen, Jos H. Beijnen, Jos H. Beijnen, Alfred H. Schinkel

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A Review of CYP3A Drug-Drug Interaction Studies: Practical Guidelines for Patients Using Targeted Oral Anticancer Drugs Dahkki Laura Molenaar-Kuijsten, Dorieke E. M. Van Balen, Jos H. Beijnen, Jos H. Beijnen, Neeltje Steeghs, Alwin D. R. Huitema, Alwin D. R. Huitema, Alwin D. R. Huitema

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ABCB1 and ABCG2 Control Brain Accumulation and Intestinal Disposition of the Novel ROS1/TRK/ALK Inhibitor Repotrectinib, While OATP1A/1B, ABCG2, and CYP3A Limit Its Oral Availabili... Dahkki Wenlong Li, Rolf W. Sparidans, Maria C. Lebre, Jos H. Beijnen, Alfred H. Schinkel

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Validation of a liquid chromatographic method for the pharmaceutical quality control of products containing elacridar Dahkki Emilia Sawicki, Michel J. Hillebrand, Hilde Rosing, Jan H.M. Schellens, Bastiaan Nuijen, Jos H. Beijnen

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Predictability of human exposure by human‐CYP3A4‐transgenic mouse models: A meta‐analysis Dahkki David Damoiseaux, Alfred H. Schinkel, Jos H. Beijnen, Alwin D. R. Huitema, Thomas P. C. Dorlo

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A poor-quality generic drug for the treatment of visceral leishmaniasis: a case report and appeal. Dahkki Thomas P C Dorlo, Teunis A Eggelte, Gerard J Schoone, Peter J de Vries, Jos H Beijnen

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P-Glycoprotein (ABCB1/MDR1) and BCRP (ABCG2) Limit Brain Accumulation and Cytochrome P450-3A (CYP3A) Restricts Oral Exposure of the RET Inhibitor Selpercatinib (RETEVMO) Dahkki Yaogeng Wang, Rolf W. Sparidans, Sander Potters, Rahime Şentürk, Maria C. Lebre, Jos H. Beijnen, Alfred H. Schinkel

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P-Glycoprotein (MDR1/ABCB1) Restricts Brain Accumulation of the Novel EGFR Inhibitor EAI045 and Oral Elacridar Coadministration Enhances Its Brain Accumulation and Oral Exposure Dahkki Jing Wang, M. Merve Susam, Changpei Gan, Rolf W. Sparidans, Maria C. Lebre, Jos H. Beijnen, Alfred H. Schinkel

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Physiologically‐based pharmacokinetic model to predict doxorubicin and paclitaxel exposure in infants through breast milk Dahkki David Damoiseaux, Frédéric Amant, Jos H. Beijnen, Shelby Barnett, Gareth J. Veal, Alwin D. R. Huitema, Thomas P. C. Dorlo

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Predictiveness of the Human-CYP3A4-Transgenic Mouse Model (Cyp3aXAV) for Human Drug Exposure of CYP3A4-Metabolized Drugs Dahkki David Damoiseaux, Wenlong Li, Alejandra Martínez-Chávez, Jos H. Beijnen, Alfred H. Schinkel, Alwin D. R. Huitema, Thomas P. C. Dorlo

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Automated synthesis and quality control of [99mTc]Tc-PSMA for radioguided surgery (in a [68Ga]Ga-PSMA workflow) Dahkki Else A. Aalbersberg, Lotte van Andel, Martine M. Geluk-Jonker, Jos H. Beijnen, Marcel P. M. Stokkel, Jeroen J. M. A. Hendrikx

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Dynamics of parasite clearance in cutaneous leishmaniasis patients treated with miltefosine. Dahkki Thomas P C Dorlo, Pieter P A M van Thiel, Gerard J Schoone, Ymkje Stienstra, Michèle van Vugt, Jos H Beijnen, Peter J de Vries

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Pharmacokinetics of Capecitabine and Four Metabolites in a Heterogeneous Population of Cancer Patients: A Comprehensive Analysis Dahkki Bart A.W. Jacobs, Maarten J. Deenen, Markus Joerger, Hilde Rosing, Niels deVries, Didier Meulendijks, Annemieke Cats, Jos H. Beijnen, Jan H.M. Schellens, Alwin D.R. Huitema

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No relation between docetaxel administration route and high‐grade diarrhea incidence Dahkki Jeroen J. M. A. Hendrikx, Frederik E. Stuurman, Ji‐Ying Song, Vincent A. deWeger, Jurjen S. Lagas, Hilde Rosing, Jos H. Beijnen, Alfred H. Schinkel, Jan H. M. Schellens, Serena Marchetti

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Longitudinal nonlinear mixed effects modeling of EGFR mutations in ctDNA as predictor of disease progression in treatment of EGFR‐mutant non‐small cell lung cancer Dahkki Julie M. Janssen, Remy B. Verheijen, Tirsa T. vanDuijl, Lishi Lin, Michel M. van denHeuvel, Jos H. Beijnen, Neeltje Steeghs, Daan van denBroek, Alwin D. R. Huitema, Thomas P. C. Dorlo

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Organic anion-transporting polypeptide 2B1 knockout and humanized mice; insights into the handling of bilirubin and drugs Dahkki Wenlong Li, Dilek Iusuf, Rolf W. Sparidans, Els Wagenaar, Yaogeng Wang, Dirk R. de Waart, Margarida L.F. Martins, Stéphanie van Hoppe, Maria C. Lebre, Olaf van Tellingen, Jos H. Beijnen, Alfred H. Schinkel

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Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism Dahkki Changpei Gan, Jing Wang, Alejandra Martínez-Chávez, Michel Hillebrand, Niels de Vries, Joke Beukers, Els Wagenaar, Yaogeng Wang, Maria C. Lebre, Hilde Rosing, Sjoerd Klarenbeek, Rahmen Bin Ali, Colin Pritchard, Ivo Huijbers, Jos H. Beijnen, Alfred H. Schinkel

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