Showing 1 - 16 results of 16 for search 'Koki Chiba', query time: 0.08s Refine Results
  1. 1
    Analysis of torsadogenic and pharmacokinetic profile of E-4031 in dogs bridging the gap of information between in vitro proarrhythmia assay and clinical observation in human subjects

    Analysis of torsadogenic and pharmacokinetic profile of E-4031 in dogs bridging the gap of information between in vitro proarrhythmia assay and clinical observation in human subjec... by Ai Goto, Hiroko Izumi-Nakaseko, Mihoko Hagiwara-Nagasawa, Koki Chiba, Kentaro Ando, Atsuhiko T. Naito, Atsushi Sugiyama

    Published 2018
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  2. 2
    Application of human induced pluripotent stem cell-derived cardiomyocytes sheets with microelectrode array system to estimate antiarrhythmic properties of multi-ion channel blockers

    Application of human induced pluripotent stem cell-derived cardiomyocytes sheets with microelectrode array system to estimate antiarrhythmic properties of multi-ion channel blocker... by Hiroko Izumi-Nakaseko, Mihoko Hagiwara-Nagasawa, Atsuhiko T. Naito, Ai Goto, Koki Chiba, Yuko Sekino, Yasunari Kanda, Atsushi Sugiyama

    Published 2018
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  3. 3
    Electropharmacological effects of intracellular Ca2+ handling modulator caldaret on the heart assessed in the halothane-anesthetized dogs

    Electropharmacological effects of intracellular Ca2+ handling modulator caldaret on the heart assessed in the halothane-anesthetized dogs by Atsushi Sugiyama, Mihoko Hagiwara-Nagasawa, Ryuichi Kambayashi, Ai Goto, Koki Chiba, Kentaro Ando, Atsuhiko T. Naito, Hiroko Izumi-Nakaseko

    Published 2019
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  4. 4
    Pharmacological β-adrenoceptor blockade can augment torsadogenic action of IKr inhibitor: Comparison of proarrhythmic effects of d-sotalol and dl-sotalol in the chronic atrioventricular block dogs

    Pharmacological β-adrenoceptor blockade can augment torsadogenic action of IKr inhibitor: Comparison of proarrhythmic effects of d-sotalol and dl-sotalol in the chronic atrioventri... by Ai Goto, Mihoko Hagiwara-Nagasawa, Koki Chiba, Ryuichi Kambayashi, Yoshio Nunoi, Hiroko Izumi-Nakaseko, Akio Matsumoto, Yasunari Kanda, Atsushi Sugiyama

    Published 2019
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  5. 5
    Analysis of electro-mechanical relationship in human iPS cell-derived cardiomyocytes sheets under proarrhythmic condition assessed by simultaneous field potential and motion vector recordings

    Analysis of electro-mechanical relationship in human iPS cell-derived cardiomyocytes sheets under proarrhythmic condition assessed by simultaneous field potential and motion vector... by Atsushi Sugiyama, Mihoko Hagiwara-Nagasawa, Ryuichi Kambayashi, Ai Goto, Koki Chiba, Atsuhiko T. Naito, Yasunari Kanda, Akio Matsumoto, Hiroko Izumi-Nakaseko

    Published 2019
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  6. 6
    Utilization of the chronic atrioventricular block cynomolgus monkey as an in vivo model to evaluate drug interaction-associated torsade de pointes

    Utilization of the chronic atrioventricular block cynomolgus monkey as an in vivo model to evaluate drug interaction-associated torsade de pointes by Ai Goto, Kengo Sakamoto, Mihoko Hagiwara-Nagasawa, Ryuichi Kambayashi, Koki Chiba, Yoshio Nunoi, Hiroko Izumi-Nakaseko, Akio Matsumoto, Atsushi Sugiyama

    Published 2020
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  7. 7
    In vivo analysis of the effects of intravenously as well as orally administered moxifloxacin on the pharmacokinetic and electrocardiographic variables along with its torsadogenic action in the chronic atrioventricular block cynomolgus monkeys

    In vivo analysis of the effects of intravenously as well as orally administered moxifloxacin on the pharmacokinetic and electrocardiographic variables along with its torsadogenic a... by Ai Goto, Kengo Sakamoto, Mihoko Hagiwara-Nagasawa, Ryuichi Kambayashi, Koki Chiba, Yoshio Nunoi, Hiroko Izumi-Nakaseko, Yoshinori Takei, Akio Matsumoto, Atsushi Sugiyama

    Published 2020
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  8. 8
    Analysis of proarrhythmic potential of an atypical antipsychotic drug paliperidone in the halothane-anesthetized dogs

    Analysis of proarrhythmic potential of an atypical antipsychotic drug paliperidone in the halothane-anesthetized dogs by Koki Chiba, Takeshi Wada, Yuji Nakamura, Xin Cao, Mihoko Hagiwara-Nagasawa, Hiroko Izumi-Nakaseko, Kentaro Ando, Koichiro Tanaka, Atsuhiko T. Naito, Atsushi Sugiyama

    Published 2017
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  9. 9
    Risperidone alone did not induce torsade de pointes: Experimental evidence from the chronic atrioventricular block model dogs

    Risperidone alone did not induce torsade de pointes: Experimental evidence from the chronic atrioventricular block model dogs by Yoshio Nunoi, Koki Chiba, Mihoko Hagiwara-Nagasawa, Ai Goto, Ryuichi Kambayashi, Hiroko Izumi-Nakaseko, Yoshinori Takei, Akio Matsumoto, Yoshinori Watanabe, Atsushi Sugiyama

    Published 2020
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  10. 10
    Characterization of microminipig as a laboratory animal for pharmacological study by analyzing bepridil-induced cardiovascular responses

    Characterization of microminipig as a laboratory animal for pharmacological study by analyzing bepridil-induced cardiovascular responses by Yoshio Nunoi, Mihoko Hagiwara-Nagasawa, Ryuichi Kambayashi, Ai Goto, Koki Chiba, Takeshi Wada, Hiroko Izumi-Nakaseko, Akio Matsumoto, Yoshinori Watanabe, Atsushi Sugiyama

    Published 2020
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  11. 11
    Use of microminipigs for unveiling unknown mechanisms of azithromycin-induced cardiovascular death

    Use of microminipigs for unveiling unknown mechanisms of azithromycin-induced cardiovascular death by Ai Goto, Mihoko Hagiwara-Nagasawa, Hiroko Izumi-Nakaseko, Kumiko Kitta, Kiyotaka Hoshiai, Koki Chiba, Kentaro Ando, Yasuki Akie, Atsuhiko T. Naito, Atsushi Sugiyama

    Published 2018
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  12. 12
    Imatinib induces diastolic dysfunction and ventricular early-repolarization delay in the halothane-anesthetized dogs: Class effects of tyrosine kinase inhibitors

    Imatinib induces diastolic dysfunction and ventricular early-repolarization delay in the halothane-anesthetized dogs: Class effects of tyrosine kinase inhibitors by Koki Chiba, Ryuichi Kambayashi, Mayu Onozato, Ai Goto, Hiroko Izumi-Nakaseko, Yoshinori Takei, Akio Matsumoto, Koichiro Tanaka, Yasunari Kanda, Takeshi Fukushima, Atsushi Sugiyama

    Published 2022
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  13. 13
    Early use of alendronate as a protective factor against the development of glucocorticoid-induced bone loss in childhood-onset rheumatic diseases: a cross-sectional study

    Early use of alendronate as a protective factor against the development of glucocorticoid-induced bone loss in childhood-onset rheumatic diseases: a cross-sectional study by Yuzaburo Inoue, Kanako Mitsunaga, Takeshi Yamamoto, Koki Chiba, Fumiya Yamaide, Taiji Nakano, Yoshinori Morita, Akiko Yamaide, Shuichi Suzuki, Takayasu Arima, Ken-ichi Yamaguchi, Minako Tomiita, Naoki Shimojo, Yoichi Kohno

    Published 2018
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  14. 14
    Changes of electrocardiogram and hemodynamics in response to dipyridamole: In vivo comparative analyses using anesthetized beagle dogs and microminipigs

    Changes of electrocardiogram and hemodynamics in response to dipyridamole: In vivo comparative analyses using anesthetized beagle dogs and microminipigs by Kentaro Ando, Akira Takahara, Yuji Nakamura, Takeshi Wada, Koki Chiba, Ai Goto, Nur Jaharat Lubna, Mihoko Hagiwara-Nagasawa, Hiroko Izumi-Nakaseko, Kiyotaka Hoshiai, Yasuki Akie, Atsuhiko T. Naito, Atsushi Sugiyama

    Published 2018
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  15. 15
    Effects of moxifloxacin on the proarrhythmic surrogate markers in healthy Filipino subjects: Exposure-response modeling using ECG data of thorough QT/QTc study

    Effects of moxifloxacin on the proarrhythmic surrogate markers in healthy Filipino subjects: Exposure-response modeling using ECG data of thorough QT/QTc study by Suchitra Matsukura, Yuji Nakamura, Kiyotaka Hoshiai, Takashi Hayashi, Tadashi Koga, Ai Goto, Koki Chiba, Nur Jaharat Lubna, Mihoko Hagiwara-Nagasawa, Hiroko Izumi-Nakaseko, Kentaro Ando, Atsuhiko T. Naito, Atsushi Sugiyama

    Published 2018
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  16. 16
    Translational Studies on Anti-Atrial Fibrillatory Action of Oseltamivir by its in vivo and in vitro Electropharmacological Analyses

    Translational Studies on Anti-Atrial Fibrillatory Action of Oseltamivir by its in vivo and in vitro Electropharmacological Analyses by Ryuichi Kambayashi, Hiroko Izumi-Nakaseko, Ai Goto, Kazuya Tsurudome, Hironori Ohshiro, Taku Izumi, Mihoko Hagiwara-Nagasawa, Koki Chiba, Ryota Nishiyama, Satomi Oyama, Yoshio Nunoi, Yoshinori Takei, Akio Matsumoto, Atsushi Sugiyama, Atsushi Sugiyama, Atsushi Sugiyama, Atsushi Sugiyama

    Published 2021
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