Search Results - Stephan Schmidt

A quantitative systems pharmacology (QSP) platform for preclinical to clinical translation of in-vivo CRISPR-Cas therapy by Devam A. Desai, Stephan Schmidt, Rodrigo Cristofoletti

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Macrolide Treatment Failure due to Drug-Drug Interactions: Real-World Evidence to Evaluate a Pharmacological Hypothesis by Brian Cicali, Stephan Schmidt, Markus Zeitlinger, Joshua D. Brown

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PK/PD modeling and simulation of the in vitro activity of the combinations of isavuconazole with echinocandins against Candida auris by Unai Caballero, Elena Eraso, Guillermo Quindós, Valvanera Vozmediano, Stephan Schmidt, Nerea Jauregizar

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Advancing drug safety science by integrating molecular knowledge with post‐marketing adverse event reports by Theodoros G. Soldatos, Sarah Kim, Stephan Schmidt, Lawrence J. Lesko, David B. Jackson

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Applying Physiologically Based Pharmacokinetic Modeling to Interpret Carbamazepine's Nonlinear Pharmacokinetics and Its Induction Potential on Cytochrome P450 3A4 and Cytochrome P4... by Xuefen Yin, Brian Cicali, Leyanis Rodriguez-Vera, Viera Lukacova, Rodrigo Cristofoletti, Stephan Schmidt

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Development of a mechanism-based pharmacokinetic/pharmacodynamic model to characterize the thermoregulatory effects of serotonergic drugs in mice by Xi-Ling Jiang, Hong-Wu Shen, Donald E. Mager, Stephan Schmidt, Ai-Ming Yu

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In Vitro Synergistic Interactions of Isavuconazole and Echinocandins against <i>Candida auris</i> by Unai Caballero, Sarah Kim, Elena Eraso, Guillermo Quindós, Valvanera Vozmediano, Stephan Schmidt, Nerea Jauregizar

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Pharmacometrics, Physiologically Based Pharmacokinetics, Quantitative Systems Pharmacology-What's Next?-Joining Mechanistic and Epidemiological Approaches by Stephan Schmidt, Sarah Kim, Valvanera Vozmediano, Rodrigo Cristofoletti, Almut G. Winterstein, Joshua D. Brown

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In Vitro Pharmacokinetic/Pharmacodynamic Modelling and Simulation of Amphotericin B against <i>Candida auris</i> by Unai Caballero, Elena Eraso, Javier Pemán, Guillermo Quindós, Valvanera Vozmediano, Stephan Schmidt, Nerea Jauregizar

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Informing the risk assessment related to lactation and drug exposure: A physiologically based pharmacokinetic lactation model for pregabalin by Cameron Humerickhouse, Michelle Pressly, Zhoumeng Lin, Daphne Guinn, Sherbet Samuels, Elimika Pfuma Fletcher, Stephan Schmidt

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Predicting Cost‐Effectiveness of Generic vs. Brand Dabigatran Using Pharmacometric Estimates Among Patients with Atrial Fibrillation in the United States by Ching‐Yu Wang, Phuong N. Pham, Sarah Kim, Karthik Lingineni, Stephan Schmidt, Vakaramoko Diaby, Joshua Brown

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Physiologically Based Pharmacokinetic Modeling of Monoclonal Antibodies in Pediatric Populations Using PK-Sim by Sumit Basu, Yi Ting (Kayla), Valvanera Vozmediano, Jan-Frederik Schlender, Thomas Eissing, Stephan Schmidt, Christoph Niederalt

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Comprehensive Physiologically Based Pharmacokinetic Model to Assess Drug-Drug Interactions of Phenytoin by Leyanis Rodriguez-Vera, Xuefen Yin, Mohammed Almoslem, Karolin Romahn, Brian Cicali, Viera Lukacova, Rodrigo Cristofoletti, Stephan Schmidt

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Model-Based Analysis of In Vivo Release Data of Levonorgestrel Implants: Projecting Long-Term Systemic Exposure by Soyoung Kim, Brian Cicali, Michelle Pressly, Lais Da Silva, Thomas Wendl, Valvanera Vozmediano, Stephan Schmidt, Rodrigo Cristofoletti

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In memoriam Lambertus ("Bert") A. Peletier 29 March 1937-16 December 2023: Furthering quantitative pharmacology through applied mathematics by Meindert Danhof, Piet H. van derGraaf, Teun M. Post, Sandra A. G. Visser, Klaas P. Zuideveld, Stephan Schmidt

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The quest for balance between capturing data and model complexity: A quantitative clinical pharmacology approach applied to monoclonal antibodies by Michelle A. Pressly, Lambertus A. Peletier, Songmao Zheng, Vishnu D. Sharma, Yi Ting (Kayla), Weirong Wang, Honghui Zhou, Stephan Schmidt

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Interspecies Brain PBPK Modeling Platform to Predict Passive Transport through the Blood-Brain Barrier and Assess Target Site Disposition by Parsshava Mehta, Amira Soliman, Leyanis Rodriguez-Vera, Stephan Schmidt, Paula Muniz, Monica Rodriguez, Marta Forcadell, Emili Gonzalez-Perez, Valvanera Vozmediano

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Development of breakthrough bleeding model of combined‐oral contraceptives utilizing model‐based meta‐analysis by Huili Chen, Dain Chun, Karthik Lingineni, Serge Guzy, Rodrigo Cristofoletti, Joachim Hoechel, Tianze Jiao, Brian Cicali, Valvanera Vozmediano, Stephan Schmidt

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Advancing Precision Medicine: A Review of Innovative In Silico Approaches for Drug Development, Clinical Pharmacology and Personalized Healthcare by Lara Marques, Bárbara Costa, Mariana Pereira, Abigail Silva, Joana Santos, Leonor Saldanha, Isabel Silva, Paulo Magalhães, Stephan Schmidt, Nuno Vale

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Experiences of persons with multiple sclerosis with rehabilitation-a qualitative interview study by Donya Ghaidar, Anna Sippel, Karin Riemann-Lorenz, Christopher Kofahl, Rebecca Morrison, Ingo Kleiter, Stephan Schmidt, Christian Dettmers, Holger Schulz, Christoph Heesen

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