Application of Physiologically Based Pharmacokinetic (PBPK) Modeling Within a Bayesian Framework to Identify Poor Metabolizers of Efavirenz (PM), Using a Test Dose of Efavirenz by Manoranjenni Chetty, Theresa Cain, Janak Wedagedera, Amin Rostami-Hodjegan, Amin Rostami-Hodjegan, Masoud Jamei

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Opening a debate on open‐source modeling tools: Pouring fuel on fire versus extinguishing the flare of a healthy debate by Amin Rostami‐Hodjegan, Frederic Y. Bois

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Editorial: Precision Medicine: Impact of Cytochromes P450 and Transporters Genetic Polymorphisms, Drug-Drug Interactions, Disease on Safety and Efficacy of Drugs by Youssef Daali, Youssef Daali, Youssef Daali, Amin Rostami-Hodjegan, Amin Rostami-Hodjegan, Caroline F. Samer, Caroline F. Samer

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Application of the Nested Enzyme‐Within‐Enterocyte (NEWE) Turnover Model for Predicting the Time Course of Pharmacodynamic Effects by Hiroyuki Takita, Adam S. Darwich, Amais Ahmad, Amin Rostami‐Hodjegan

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Seeing what is behind the smokescreen: A systematic review of methodological aspects of smoking interaction studies over the last three decades and implications for future clinical... by Robert Hermann, Amin Rostami‐Hodjegan, Ping Zhao, Isabelle Ragueneau‐Majlessi

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Precision dosing to avoid adverse drug reactions by Thomas M. Polasek, Carl M. J. Kirkpatrick, Amin Rostami-Hodjegan

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Population pharmacokinetic modeling and simulation to support qualification of pyridoxic acid as endogenous biomarker of OAT1/3 renal transporters by Amais Ahmad, Kayode Ogungbenro, Annett Kunze, Frank Jacobs, Jan Snoeys, Amin Rostami‐Hodjegan, Aleksandra Galetin

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Understanding Discordance between In Vitro Dissolution, Local Gut and Systemic Bioequivalence of Budesonide in Healthy and Crohn's Disease Patients through PBPK Modeling by Chunyan Han, Tiancheng Sun, Siri Kalyan Chirumamilla, Frederic Y. Bois, Mandy Xu, Amin Rostami-Hodjegan

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A close examination of BCRP's role in lactation and methods for predicting drug distribution into milk by Caroline Sychterz, Hong Shen, Yueping Zhang, Michael Sinz, Amin Rostami‐Hodjegan, Brian J. Schmidt, Lu Gaohua, Aleksandra Galetin

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Mechanistic Models as Framework for Understanding Biomarker Disposition: Prediction of Creatinine‐Drug Interactions by Daniel Scotcher, Vikram Arya, Xinning Yang, Ping Zhao, Lei Zhang, Shiew‐Mei Huang, Amin Rostami‐Hodjegan, Aleksandra Galetin

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A Novel Physiologically Based Model of Creatinine Renal Disposition to Integrate Current Knowledge of Systems Parameters and Clinical Observations by Daniel Scotcher, Vikram Arya, Xinning Yang, Ping Zhao, Lei Zhang, Shiew‐Mei Huang, Amin Rostami‐Hodjegan, Aleksandra Galetin

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Delineating gene-environment effects using virtual twins of patients treated with clozapine by Sam Mostafa, Thomas M. Polasek, Chad Bousman, Amin Rostami‐Hodjegan, Leslie J. Sheffield, Ian Everall, Christos Pantelis, Carl M. J. Kirkpatrick

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A guide to developing population files for physiologically‐based pharmacokinetic modeling in the Simcyp Simulator by Liam Curry, Sarah Alrubia, Frederic Y. Bois, Ruth Clayton, Eman El‐Khateeb, Trevor N. Johnson, Muhammad Faisal, Sibylle Neuhoff, Kris Wragg, Amin Rostami‐Hodjegan

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Virtual twins for model‐informed precision dosing of clozapine in patients with treatment‐resistant schizophrenia by Sam Mostafa, Reza Rafizadeh, Thomas M. Polasek, Chad A. Bousman, Amin Rostami‐Hodjegan, Robert Stowe, Prescilla Carrion, Leslie J. Sheffield, Carl M. J. Kirkpatrick

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