Search Results - Charlotte Kloft

Cell‐level systems biology model to study inflammatory bowel diseases and their treatment options by Sabine Stübler, Charlotte Kloft, Wilhelm Huisinga

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What "Impact" Do NLME Publications Have Outside Our Community? by Stefanie Hennig, Julia Fischer, Charlotte Kloft

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Deriving mechanism‐based pharmacodynamic models by reducing quantitative systems pharmacology models: An application to warfarin by Undine Falkenhagen, Jane Knöchel, Charlotte Kloft, Wilhelm Huisinga

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Bayesian Data Assimilation to Support Informed Decision Making in Individualized Chemotherapy by Corinna Maier, Niklas Hartung, Jana deWiljes, Charlotte Kloft, Wilhelm Huisinga

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Reinforcement learning and Bayesian data assimilation for model‐informed precision dosing in oncology by Corinna Maier, Niklas Hartung, Charlotte Kloft, Wilhelm Huisinga, Jana deWiljes

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A continued learning approach for model‐informed precision dosing: Updating models in clinical practice by Corinna Maier, Jana deWiljes, Niklas Hartung, Charlotte Kloft, Wilhelm Huisinga

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Towards the Elucidation of the Pharmacokinetics of Voriconazole: A Quantitative Characterization of Its Metabolism by Josefine Schulz, Antonia Thomas, Ayatallah Saleh, Gerd Mikus, Charlotte Kloft, Robin Michelet

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Novel Pharmacokinetic/Pharmacodynamic Parameters Quantify the Exposure-Effect Relationship of Levofloxacin against Fluoroquinolone-Resistant <i>Escherichia coli</i> by Johanna Seeger, Sebastian Guenther, Katharina Schaufler, Stefan E. Heiden, Robin Michelet, Charlotte Kloft

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Semimechanistic Clearance Models of Oncology Biotherapeutics and Impact of Study Design: Cetuximab as a Case Study by Ana‐Marija Grisic, Akash Khandelwal, Mauro Bertolino, Wilhelm Huisinga, Pascal Girard, Charlotte Kloft

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A Model-Based Pharmacokinetic/Pharmacodynamic Analysis of the Combination of Amoxicillin and Monophosphoryl Lipid A Against <i>S. pneumoniae</i> in Mice by Sebastian Franck, Robin Michelet, Fiordiligie Casilag, Jean-Claude Sirard, Sebastian G. Wicha, Charlotte Kloft

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Development of a Model-Informed Dosing Tool to Optimise Initial Antibiotic Dosing-A Translational Example for Intensive Care Units by Ferdinand Anton Weinelt, Miriam Songa Stegemann, Anja Theloe, Frieder Pfäfflin, Stephan Achterberg, Lisa Schmitt, Wilhelm Huisinga, Robin Michelet, Stefanie Hennig, Charlotte Kloft

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A prognostic baseline blood biomarker and tumor growth kinetics integrated model in paclitaxel/platinum treated advanced non‐small cell lung cancer patients by Francis Williams Ojara, Andrea Henrich, Nicolas Frances, Yomna M. Nassar, Wilhelm Huisinga, Niklas Hartung, Kimberly Geiger, Stefan Holdenrieder, Markus Joerger, Charlotte Kloft

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Integrated Data Analysis of Six Clinical Studies Points Toward Model-Informed Precision Dosing of Tamoxifen by Lena Klopp-Schulze, Anna Mueller-Schoell, Anna Mueller-Schoell, Patrick Neven, Stijn L. W. Koolen, Ron H. J. Mathijssen, Markus Joerger, Charlotte Kloft

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Simulation-Based Assessment of the Impact of Non-Adherence on Endoxifen Target Attainment in Different Tamoxifen Dosing Strategies by Anna Mueller-Schoell, Lena Klopp-Schulze, Robin Michelet, Madelé van Dyk, Thomas E. Mürdter, Matthias Schwab, Markus Joerger, Wilhelm Huisinga, Gerd Mikus, Charlotte Kloft

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Meropenem Plasma and Interstitial Soft Tissue Concentrations in Obese and Nonobese Patients-A Controlled Clinical Trial by Philipp Simon, David Petroff, David Busse, Jana Heyne, Felix Girrbach, Arne Dietrich, Alexander Kratzer, Markus Zeitlinger, Charlotte Kloft, Frieder Kees, Hermann Wrigge, Christoph Dorn

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Ulcerative Colitis and Acute Severe Ulcerative Colitis Patients Are Overlooked in Infliximab Population Pharmacokinetic Models: Results from a Comprehensive Review by Alix Démaris, Ella S. K. Widigson, Johan F. K. F. Ilvemark, Casper Steenholdt, Jakob B. Seidelin, Wilhelm Huisinga, Robin Michelet, Linda B. S. Aulin, Charlotte Kloft

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Similar Piperacillin/Tazobactam Target Attainment in Obese versus Nonobese Patients despite Differences in Interstitial Tissue Fluid Pharmacokinetics by David Busse, Philipp Simon, David Petroff, Christoph Dorn, Lisa Schmitt, Davide Bindellini, Alexander Kratzer, Arne Dietrich, Markus Zeitlinger, Wilhelm Huisinga, Robin Michelet, Hermann Wrigge, Charlotte Kloft

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Model-Informed Target Morning 17α-Hydroxyprogesterone Concentrations in Dried Blood Spots for Pediatric Congenital Adrenal Hyperplasia Patients by Viktoria Stachanow, Uta Neumann, Oliver Blankenstein, Nele Alder-Baerens, Davide Bindellini, Peter Hindmarsh, Richard J. Ross, Martin J. Whitaker, Johanna Melin, Wilhelm Huisinga, Robin Michelet, Charlotte Kloft

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Barriers to global pharmacometrics: educational challenges and opportunities across the globe by Robin Michelet, Linda B. S. Aulin, Jens M. Borghardt, Teresa Dalla Costa, Paolo Denti, Manuel Ibarra, Guangda Ma, Bernd Meibohm, Goonaseelan (Colin), Stephan Schmidt, Stefanie Hennig, Charlotte Kloft

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Evaluation of the MeroRisk Calculator, A User-Friendly Tool to Predict the Risk of Meropenem Target Non-Attainment in Critically Ill Patients by Uwe Liebchen, Marian Klose, Michael Paal, Michael Vogeser, Michael Zoller, Ines Schroeder, Lisa Schmitt, Wilhelm Huisinga, Robin Michelet, Johannes Zander, Christina Scharf, Ferdinand A. Weinelt, Charlotte Kloft

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