Search Results - Conor R. Caffrey

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  1. 1
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    Cure of hookworm infection with a cysteine protease inhibitor. by Jon J Vermeire, Lorine D Lantz, Conor R Caffrey

    Published 2012
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  2. 2
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    Odanacatib, a Cathepsin K Cysteine Protease Inhibitor, Kills Hookworm In Vivo by Jon J. Vermeire, Brian M. Suzuki, Conor R. Caffrey

    Published 2016
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  3. 3
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    Octopamine signaling in the metazoan pathogen Schistosoma mansoni: localization, small-molecule screening and opportunities for drug development by Nelly El-Sakkary, Steven Chen, Michelle R. Arkin, Conor R. Caffrey, Paula Ribeiro

    Published 2018
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  4. 4
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    Cysteine proteases as digestive enzymes in parasitic helminths. by Conor R Caffrey, Louise Goupil, Karina M Rebello, John P Dalton, David Smith

    Published 2018
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  5. 5
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    Proteomic identification of IPSE/alpha-1 as a major hepatotoxin secreted by Schistosoma mansoni eggs. by Maha-Hamadien Abdulla, Kee-Chong Lim, James H McKerrow, Conor R Caffrey

    Published 2011
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  6. 6
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    A global comparison of the human and T. brucei degradomes gives insights about possible parasite drug targets. by Susan T Mashiyama, Kyriacos Koupparis, Conor R Caffrey, James H McKerrow, Patricia C Babbitt

    Published 2012
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  7. 7
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    A secreted schistosome cathepsin B1 cysteine protease and acute schistosome infection induce a transient T helper 17 response. by Kateryna Soloviova, Ellen C Fox, John P Dalton, Conor R Caffrey, Stephen J Davies

    Published 2019
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  8. 8
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    Cysteine proteases during larval migration and development of helminths in their final host. by Alexandra Grote, Conor R Caffrey, Karina M Rebello, David Smith, John P Dalton, Sara Lustigman

    Published 2018
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  9. 9
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    Evaluation of the CCA Immuno-Chromatographic Test to Diagnose Schistosoma mansoni in Minas Gerais State, Brazil. by Alda Maria Soares Silveira, Emanuele Gama Dutra Costa, Debalina Ray, Brian M Suzuki, Michael H Hsieh, Lucia Alves de Oliveira Fraga, Conor R Caffrey

    Published 2016
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  10. 10
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    Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors. by Pavla Fajtová, Saša Štefanić, Martin Hradilek, Jan Dvořák, Jiří Vondrášek, Adéla Jílková, Lenka Ulrychová, James H McKerrow, Conor R Caffrey, Michael Mareš, Martin Horn

    Published 2015
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  11. 11
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    Synthesis and Bioactivity of Phthalimide Analogs as Potential Drugs to Treat Schistosomiasis, a Neglected Disease of Poverty by Snigdha Singh, Nelly El-Sakkary, Danielle E. Skinner, Prem Prakash Sharma, Sabine Ottilie, Yevgeniya Antonova-Koch, Prashant Kumar, Elizabeth Winzeler, Poonam, Conor R. Caffrey, Brijesh Rathi

    Published 2020
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  12. 12
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    Drug discovery for schistosomiasis: hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening. by Maha-Hamadien Abdulla, Debbie S Ruelas, Brian Wolff, June Snedecor, Kee-Chong Lim, Fengyun Xu, Adam R Renslo, Janice Williams, James H McKerrow, Conor R Caffrey

    Published 2009
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  13. 13
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    RNA interference in Schistosoma mansoni schistosomula: selectivity, sensitivity and operation for larger-scale screening. by Saša Stefanić, Jan Dvořák, Martin Horn, Simon Braschi, Daniel Sojka, Debbie S Ruelas, Brian Suzuki, Kee-Chong Lim, Stephanie D Hopkins, James H McKerrow, Conor R Caffrey

    Published 2010
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  14. 14
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    Sex-Biased Transcriptome of Schistosoma mansoni: Host-Parasite Interaction, Genetic Determinants and Epigenetic Regulators Are Associated with Sexual Differentiation. by Marion A L Picard, Jérôme Boissier, David Roquis, Christoph Grunau, Jean-François Allienne, David Duval, Eve Toulza, Nathalie Arancibia, Conor R Caffrey, Thavy Long, Sabine Nidelet, Marine Rohmer, Céline Cosseau

    Published 2016
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  15. 15
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    Dissecting the active site of the collagenolytic cathepsin L3 protease of the invasive stage of Fasciola hepatica. by Ileana Corvo, Anthony J O'Donoghue, Lucía Pastro, Natalia Pi-Denis, Alegra Eroy-Reveles, Leda Roche, James H McKerrow, John P Dalton, Charles S Craik, Conor R Caffrey, José F Tort

    Published 2013
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  16. 16
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    SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties. by Adrian Leontovyč, Lenka Ulrychová, Anthony J O'Donoghue, Jiří Vondrášek, Lucie Marešová, Martin Hubálek, Pavla Fajtová, Marta Chanová, Zhenze Jiang, Charles S Craik, Conor R Caffrey, Michael Mareš, Jan Dvořák, Martin Horn

    Published 2018
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  17. 17
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    Structure-Bioactivity Relationship for Benzimidazole Thiophene Inhibitors of Polo-Like Kinase 1 (PLK1), a Potential Drug Target in Schistosoma mansoni. by Thavy Long, R Jeffrey Neitz, Rachel Beasley, Chakrapani Kalyanaraman, Brian M Suzuki, Matthew P Jacobson, Colette Dissous, James H McKerrow, David H Drewry, William J Zuercher, Rahul Singh, Conor R Caffrey

    Published 2016
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  18. 18
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    Trypsin- and Chymotrypsin-like serine proteases in schistosoma mansoni-- 'the undiscovered country'. by Martin Horn, Pavla Fajtová, Liliana Rojo Arreola, Lenka Ulrychová, Pavla Bartošová-Sojková, Zdeněk Franta, Anna V Protasio, David Opavský, Jiří Vondrášek, James H McKerrow, Michael Mareš, Conor R Caffrey, Jan Dvořák

    Published 2014
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  19. 19
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    SmCL3, a gastrodermal cysteine protease of the human blood fluke Schistosoma mansoni. by Jan Dvorák, Susan T Mashiyama, Mohammed Sajid, Simon Braschi, Melaine Delcroix, Eric L Schneider, Wilson H McKerrow, Mahmoud Bahgat, Elizabeth Hansell, Patricia C Babbitt, Charles S Craik, James H McKerrow, Conor R Caffrey

    Published 2009
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  20. 20
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    Design, synthesis, and in vitro evaluation of aza-peptide aldehydes and ketones as novel and selective protease inhibitors by Thomas S. Corrigan, Leilani M. Lotti Diaz, Sarah E. Border, Steven C. Ratigan, Kayla Q. Kasper, Daniel Sojka, Pavla Fajtova, Conor R. Caffrey, Guy S. Salvesen, Craig A. McElroy, Christopher M. Hadad, Özlem Doğan Ekici

    Published 2020
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