Search Results - James H McKerrow

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  1. 1
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    Update on drug development targeting parasite cysteine proteases. by James H McKerrow

    Published 2018
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  2. 2
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    The diverse roles of cysteine proteases in parasites and their suitability as drug targets. by James H McKerrow

    Published 2018
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  3. 3
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    Proteomic identification of IPSE/alpha-1 as a major hepatotoxin secreted by Schistosoma mansoni eggs. by Maha-Hamadien Abdulla, Kee-Chong Lim, James H McKerrow, Conor R Caffrey

    Published 2011
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  4. 4
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    A global comparison of the human and T. brucei degradomes gives insights about possible parasite drug targets. by Susan T Mashiyama, Kyriacos Koupparis, Conor R Caffrey, James H McKerrow, Patricia C Babbitt

    Published 2012
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  5. 5
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    Delineation of diverse macrophage activation programs in response to intracellular parasites and cytokines. by Shuyi Zhang, Charles C Kim, Sajeev Batra, James H McKerrow, P'ng Loke

    Published 2010
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  6. 6
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    Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and fluconazole. by Chiung-Kuang Chen, Siegfried S F Leung, Christophe Guilbert, Matthew P Jacobson, James H McKerrow, Larissa M Podust

    Published 2010
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  7. 7
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    RNA interference of Trypanosoma brucei cathepsin B and L affects disease progression in a mouse model. by Maha-Hamadien Abdulla, Theresa O'Brien, Zachary B Mackey, Mohamed Sajid, Dennis J Grab, James H McKerrow

    Published 2008
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  8. 8
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    Activity profiling of peptidases in Angiostrongylus costaricensis first-stage larvae and adult worms. by Karina M Rebello, James H McKerrow, Ester M Mota, Anthony J O Donoghue, Ana Gisele C Neves-Ferreira

    Published 2018
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  9. 9
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    A screen against Leishmania intracellular amastigotes: comparison to a promastigote screen and identification of a host cell-specific hit. by Geraldine De Muylder, Kenny K H Ang, Steven Chen, Michelle R Arkin, Juan C Engel, James H McKerrow

    Published 2011
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  10. 10
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    In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi. by Yen Ting Chen, Linda S Brinen, Iain D Kerr, Elizabeth Hansell, Patricia S Doyle, James H McKerrow, William R Roush

    Published 2010
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  11. 11
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    Long term follow-up of Trypanosoma cruzi infection and Chagas disease manifestations in mice treated with benznidazole or posaconazole. by Claudia Magalhães Calvet, Tatiana Araújo Silva, Diane Thomas, Brian Suzuki, Ken Hirata, Jair Lage Siqueira-Neto, James H McKerrow

    Published 2020
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  12. 12
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    Spatial metabolomics identifies localized chemical changes in heart tissue during chronic cardiac Chagas Disease. by Danya A Dean, Gautham Gautham, Jair L Siqueira-Neto, James H McKerrow, Pieter C Dorrestein, Laura-Isobel McCall

    Published 2021
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  13. 13
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    Cysteine and Aspartyl Proteases Contribute to Protein Digestion in the Gut of Freshwater Planaria. by Louise S Goupil, Sam L Ivry, Ivy Hsieh, Brian M Suzuki, Charles S Craik, Anthony J O'Donoghue, James H McKerrow

    Published 2016
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  14. 14
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    Proteomic analysis of skin invasion by blood fluke larvae. by Elizabeth Hansell, Simon Braschi, Katalin F Medzihradszky, Mohammed Sajid, Moumita Debnath, Jessica Ingram, K C Lim, James H McKerrow

    Published 2008
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  15. 15
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    Molecular dissection of Chagas induced cardiomyopathy reveals central disease associated and druggable signaling pathways. by Jacob M Wozniak, Tatiana Araújo Silva, Diane Thomas, Jair L Siqueira-Neto, James H McKerrow, David J Gonzalez, Claudia M Calvet

    Published 2020
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  16. 16
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    Trypanosoma cruzi CYP51 inhibitor derived from a Mycobacterium tuberculosis screen hit. by Chiung-Kuang Chen, Patricia S Doyle, Liudmila V Yermalitskaya, Zachary B Mackey, Kenny K H Ang, James H McKerrow, Larissa M Podust

    Published 2009
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  17. 17
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    Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors. by Pavla Fajtová, Saša Štefanić, Martin Hradilek, Jan Dvořák, Jiří Vondrášek, Adéla Jílková, Lenka Ulrychová, James H McKerrow, Conor R Caffrey, Michael Mareš, Martin Horn

    Published 2015
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  18. 18
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    CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM). by Anjan Debnath, Claudia M Calvet, Gareth Jennings, Wenxu Zhou, Alexander Aksenov, Madeline R Luth, Ruben Abagyan, W David Nes, James H McKerrow, Larissa M Podust

    Published 2017
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  19. 19
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    Drug discovery for schistosomiasis: hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening. by Maha-Hamadien Abdulla, Debbie S Ruelas, Brian Wolff, June Snedecor, Kee-Chong Lim, Fengyun Xu, Adam R Renslo, Janice Williams, James H McKerrow, Conor R Caffrey

    Published 2009
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  20. 20
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    RNA interference in Schistosoma mansoni schistosomula: selectivity, sensitivity and operation for larger-scale screening. by Saša Stefanić, Jan Dvořák, Martin Horn, Simon Braschi, Daniel Sojka, Debbie S Ruelas, Brian Suzuki, Kee-Chong Lim, Stephanie D Hopkins, James H McKerrow, Conor R Caffrey

    Published 2010
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