Search Results - Wilhelm Huisinga

Cell‐level systems biology model to study inflammatory bowel diseases and their treatment options by Sabine Stübler, Charlotte Kloft, Wilhelm Huisinga

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Deriving mechanism‐based pharmacodynamic models by reducing quantitative systems pharmacology models: An application to warfarin by Undine Falkenhagen, Jane Knöchel, Charlotte Kloft, Wilhelm Huisinga

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Nonparametric goodness‐of‐fit testing for parametric covariate models in pharmacometric analyses by Niklas Hartung, Martin Wahl, Abhishake Rastogi, Wilhelm Huisinga

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Bayesian Data Assimilation to Support Informed Decision Making in Individualized Chemotherapy by Corinna Maier, Niklas Hartung, Jana deWiljes, Charlotte Kloft, Wilhelm Huisinga

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Reinforcement learning and Bayesian data assimilation for model‐informed precision dosing in oncology by Corinna Maier, Niklas Hartung, Charlotte Kloft, Wilhelm Huisinga, Jana deWiljes

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A continued learning approach for model‐informed precision dosing: Updating models in clinical practice by Corinna Maier, Jana deWiljes, Niklas Hartung, Charlotte Kloft, Wilhelm Huisinga

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Semimechanistic Clearance Models of Oncology Biotherapeutics and Impact of Study Design: Cetuximab as a Case Study by Ana‐Marija Grisic, Akash Khandelwal, Mauro Bertolino, Wilhelm Huisinga, Pascal Girard, Charlotte Kloft

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Development of a Model-Informed Dosing Tool to Optimise Initial Antibiotic Dosing-A Translational Example for Intensive Care Units by Ferdinand Anton Weinelt, Miriam Songa Stegemann, Anja Theloe, Frieder Pfäfflin, Stephan Achterberg, Lisa Schmitt, Wilhelm Huisinga, Robin Michelet, Stefanie Hennig, Charlotte Kloft

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A prognostic baseline blood biomarker and tumor growth kinetics integrated model in paclitaxel/platinum treated advanced non‐small cell lung cancer patients by Francis Williams Ojara, Andrea Henrich, Nicolas Frances, Yomna M. Nassar, Wilhelm Huisinga, Niklas Hartung, Kimberly Geiger, Stefan Holdenrieder, Markus Joerger, Charlotte Kloft

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Simulation-Based Assessment of the Impact of Non-Adherence on Endoxifen Target Attainment in Different Tamoxifen Dosing Strategies by Anna Mueller-Schoell, Lena Klopp-Schulze, Robin Michelet, Madelé van Dyk, Thomas E. Mürdter, Matthias Schwab, Markus Joerger, Wilhelm Huisinga, Gerd Mikus, Charlotte Kloft

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Ulcerative Colitis and Acute Severe Ulcerative Colitis Patients Are Overlooked in Infliximab Population Pharmacokinetic Models: Results from a Comprehensive Review by Alix Démaris, Ella S. K. Widigson, Johan F. K. F. Ilvemark, Casper Steenholdt, Jakob B. Seidelin, Wilhelm Huisinga, Robin Michelet, Linda B. S. Aulin, Charlotte Kloft

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Similar Piperacillin/Tazobactam Target Attainment in Obese versus Nonobese Patients despite Differences in Interstitial Tissue Fluid Pharmacokinetics by David Busse, Philipp Simon, David Petroff, Christoph Dorn, Lisa Schmitt, Davide Bindellini, Alexander Kratzer, Arne Dietrich, Markus Zeitlinger, Wilhelm Huisinga, Robin Michelet, Hermann Wrigge, Charlotte Kloft

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Model-Informed Target Morning 17α-Hydroxyprogesterone Concentrations in Dried Blood Spots for Pediatric Congenital Adrenal Hyperplasia Patients by Viktoria Stachanow, Uta Neumann, Oliver Blankenstein, Nele Alder-Baerens, Davide Bindellini, Peter Hindmarsh, Richard J. Ross, Martin J. Whitaker, Johanna Melin, Wilhelm Huisinga, Robin Michelet, Charlotte Kloft

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Evaluation of the MeroRisk Calculator, A User-Friendly Tool to Predict the Risk of Meropenem Target Non-Attainment in Critically Ill Patients by Uwe Liebchen, Marian Klose, Michael Paal, Michael Vogeser, Michael Zoller, Ines Schroeder, Lisa Schmitt, Wilhelm Huisinga, Robin Michelet, Johannes Zander, Christina Scharf, Ferdinand A. Weinelt, Charlotte Kloft

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Insights in the maturational processes influencing hydrocortisone pharmacokinetics in congenital adrenal hyperplasia patients using a middle-out approach by Robin Michelet, Davide Bindellini, Davide Bindellini, Johanna Melin, Johanna Melin, Uta Neumann, Oliver Blankenstein, Wilhelm Huisinga, Trevor N. Johnson, Martin J. Whitaker, Richard Ross, Richard Ross, Charlotte Kloft

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Exploring Dried Blood Spot Cortisol Concentrations as an Alternative for Monitoring Pediatric Adrenal Insufficiency Patients: A Model-Based Analysis by Viktoria Stachanow, Viktoria Stachanow, Uta Neumann, Oliver Blankenstein, Oliver Blankenstein, Davide Bindellini, Davide Bindellini, Johanna Melin, Johanna Melin, Richard Ross, Martin J. Whitaker, Wilhelm Huisinga, Robin Michelet, Charlotte Kloft

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Evaluation of a Meropenem and Piperacillin Monitoring Program in Intensive Care Unit Patients Calls for the Regular Assessment of Empirical Targets and Easy-to-Use Dosing Decision... by Ferdinand Anton Weinelt, Miriam Songa Stegemann, Anja Theloe, Frieder Pfäfflin, Stephan Achterberg, Franz Weber, Lucas Dübel, Agata Mikolajewska, Alexander Uhrig, Peggy Kiessling, Wilhelm Huisinga, Robin Michelet, Stefanie Hennig, Charlotte Kloft

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