Rezultaty - Trevor N. Johnson

Development and application of a pediatric mechanistic kidney model od Farzaneh Salem, Ben G. Small, Trevor N. Johnson

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Physiologically Based Pharmacokinetics Modeling in the Neonatal Population-Current Advances, Challenges, and Opportunities od Jean Dinh, Trevor N. Johnson, Manuela Grimstein, Tamorah Lewis

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Increasing application of pediatric physiologically based pharmacokinetic models across academic and industry organizations od Trevor N. Johnson, Ben G. Small, Karen Rowland Yeo

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Physiologically Based Pharmacokinetic Modelling to Predict Imatinib Exposures in Cancer Patients with Renal Dysfunction: A Case Study od Karen Rowland Yeo, Oliver Hatley, Ben G. Small, Trevor N. Johnson

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A best practice framework for applying physiologically‐based pharmacokinetic modeling to pediatric drug development od Trevor N. Johnson, Ben G. Small, Eva Gil Berglund, Karen Rowland Yeo

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Combining data on the bioavailability of midazolam and physiologically‐based pharmacokinetic modeling to investigate intestinal CYP3A4 ontogeny od Trevor N. Johnson, Hannah K. Batchelor, Jan Goelen, Richard D. Horniblow, Jean Dinh

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Using a Vancomycin PBPK Model in Special Populations to Elucidate Case‐Based Clinical PK Observations od Chie Emoto, Trevor N. Johnson, Brooks T. McPhail, Alexander A. Vinks, Tsuyoshi Fukuda

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PBPK Model of Morphine Incorporating Developmental Changes in Hepatic OCT1 and UGT2B7 Proteins to Explain the Variability in Clearances in Neonates and Small Infants od Chie Emoto, Trevor N. Johnson, Sibylle Neuhoff, David Hahn, Alexander A. Vinks, Tsuyoshi Fukuda

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A Theoretical Physiologically‐Based Pharmacokinetic Approach to Ascertain Covariates Explaining the Large Interpatient Variability in Tacrolimus Disposition od Chie Emoto, Trevor N. Johnson, David Hahn, Uwe Christians, Rita R. Alloway, Alexander A. Vinks, Tsuyoshi Fukuda

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Forecasting Fetal Buprenorphine Exposure through Maternal-Fetal Physiologically Based Pharmacokinetic Modeling od Matthijs W. van Hoogdalem, Ryota Tanaka, Khaled Abduljalil, Trevor N. Johnson, Scott L. Wexelblatt, Henry T. Akinbi, Alexander A. Vinks, Tomoyuki Mizuno

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A guide to developing population files for physiologically‐based pharmacokinetic modeling in the Simcyp Simulator od Liam Curry, Sarah Alrubia, Frederic Y. Bois, Ruth Clayton, Eman El‐Khateeb, Trevor N. Johnson, Muhammad Faisal, Sibylle Neuhoff, Kris Wragg, Amin Rostami‐Hodjegan

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Are body surface area based estimates of liver volume applicable to children with overweight or obesity? An in vivo validation study od Chelsea Hosey‐Cojocari, Sherwin S. Chan, Chance S. Friesen, Amie Robinson, Veronica Williams, Erica Swanson, Daniel O'Toole, Jansynn Radford, Neil Mardis, Trevor N. Johnson, J. Steven Leeder, Valentina Shakhnovich

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Insights in the maturational processes influencing hydrocortisone pharmacokinetics in congenital adrenal hyperplasia patients using a middle-out approach od Robin Michelet, Davide Bindellini, Davide Bindellini, Johanna Melin, Johanna Melin, Uta Neumann, Oliver Blankenstein, Wilhelm Huisinga, Trevor N. Johnson, Martin J. Whitaker, Richard Ross, Richard Ross, Charlotte Kloft

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Pediatric Pharmacokinetics and Dose Predictions: A Report of a Satellite Meeting to the 10th Juvenile Toxicity Symposium od Bianca D. vanGroen, Venkatesh Pilla Reddy, Justine Badée, Andrés Olivares‐Morales, Trevor N. Johnson, Johan Nicolaï, Pieter Annaert, Anne Smits, Saskia N. deWildt, Catherijne A. J. Knibbe, Loeckie deZwart

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