Showing 1 - 19 results of 19 for search 'Hatem A. Abdel-Aziz', query time: 0.12s Refine Results
  1. 1
    Design, Synthesis and Biological Assessment of <i>N</i>'-(2-Oxoindolin-3-ylidene)-6-methylimidazo[2,1-<i>b</i>]thiazole-5-carbohydrazides as Potential Anti-Proliferative Agents toward MCF-7 Breast Cancer

    Design, Synthesis and Biological Assessment of <i>N</i>'-(2-Oxoindolin-3-ylidene)-6-methylimidazo[2,1-<i>b</i>]thiazole-5-carbohydrazides as Potential Anti-Proliferative Agents tow... by Najla A. Alshaye, Mohamed K. Elgohary, Mahmoud S. Elkotamy, Hatem A. Abdel-Aziz

    Published 2024
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  2. 2
    One-pot three-component synthesis of novel spirooxindoles with potential cytotoxic activity against triple-negative breast cancer MDA-MB-231 cells

    One-pot three-component synthesis of novel spirooxindoles with potential cytotoxic activity against triple-negative breast cancer MDA-MB-231 cells by Wagdy M. Eldehna, Dina H. EL-Naggar, Ahmed R. Hamed, Hany S. Ibrahim, Hazem A. Ghabbour, Hatem A. Abdel-Aziz

    Published 2018
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  3. 3
    Discovery of 3,6-disubstituted pyridazines as a novel class of anticancer agents targeting cyclin-dependent kinase 2: synthesis, biological evaluation and in silico insights

    Discovery of 3,6-disubstituted pyridazines as a novel class of anticancer agents targeting cyclin-dependent kinase 2: synthesis, biological evaluation and in silico insights by Ahmed Sabt, Wagdy M. Eldehna, Tarfah Al-Warhi, Ohoud J. Alotaibi, Mahmoud M. Elaasser, Howayda Suliman, Hatem A. Abdel-Aziz

    Published 2020
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  4. 4
    Synthesis and biological evaluation of certain hydrazonoindolin-2-one derivatives as new potent anti-proliferative agents

    Synthesis and biological evaluation of certain hydrazonoindolin-2-one derivatives as new potent anti-proliferative agents by Wagdy M. Eldehna, Reem I. Al-Wabli, Maha S. Almutairi, Adam B. Keeton, Gary A. Piazza, Hatem A. Abdel-Aziz, Mohamed I. Attia

    Published 2018
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  5. 5
    Novel benzofuran-based sulphonamides as selective carbonic anhydrases IX and XII inhibitors: synthesis and in vitro biological evaluation

    Novel benzofuran-based sulphonamides as selective carbonic anhydrases IX and XII inhibitors: synthesis and in vitro biological evaluation by Mohamed A. Abdelrahman, Wagdy M. Eldehna, Alessio Nocentini, Hany S. Ibrahim, Hadia Almahli, Hatem A. Abdel-Aziz, Sahar M. Abou-Seri, Claudiu T. Supuran

    Published 2020
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  6. 6
    Effect of hydrophobic extension of aryl enaminones and pyrazole-linked compounds combined with sulphonamide, sulfaguanidine, or carboxylic acid functionalities on carbonic anhydrase inhibitory potency and selectivity

    Effect of hydrophobic extension of aryl enaminones and pyrazole-linked compounds combined with sulphonamide, sulfaguanidine, or carboxylic acid functionalities on carbonic anhydras... by Heba Abdelrasheed Allam, Mohamed E. Albakry, Walaa R. Mahmoud, Alessandro Bonardi, Shaimaa A. Moussa, Samy Mohamady, Hatem A. Abdel-Aziz, Claudiu T. Supuran, Hany S. Ibrahim

    Published 2023
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  7. 7
    Synthesis and in vitro anticancer activity of certain novel 1-(2-methyl-6-arylpyridin-3-yl)-3-phenylureas as apoptosis-inducing agents

    Synthesis and in vitro anticancer activity of certain novel 1-(2-methyl-6-arylpyridin-3-yl)-3-phenylureas as apoptosis-inducing agents by Wagdy M. Eldehna, Ghada S. Hassan, Sara T. Al-Rashood, Tarfah Al-Warhi, Ahmed E. Altyar, Hamad M. Alkahtani, Abdulrahman A. Almehizia, Hatem A. Abdel-Aziz

    Published 2019
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  8. 8
    Synthesis and in vitro anti-proliferative activity of some novel isatins conjugated with quinazoline/phthalazine hydrazines against triple-negative breast cancer MDA-MB-231 cells as apoptosis-inducing agents

    Synthesis and in vitro anti-proliferative activity of some novel isatins conjugated with quinazoline/phthalazine hydrazines against triple-negative breast cancer MDA-MB-231 cells a... by Wagdy M. Eldehna, Hadia Almahli, Ghada H. Al-Ansary, Hazem A. Ghabbour, Mohamed H. Aly, Omnia E. Ismael, Abdullah Al-Dhfyan, Hatem A. Abdel-Aziz

    Published 2017
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  9. 9
    Identification of 3-(piperazinylmethyl)benzofuran derivatives as novel type II CDK2 inhibitors: design, synthesis, biological evaluation, and in silico insights

    Identification of 3-(piperazinylmethyl)benzofuran derivatives as novel type II CDK2 inhibitors: design, synthesis, biological evaluation, and in silico insights by Wagdy M. Eldehna, Raed M. Maklad, Hadia Almahli, Tarfah Al-Warhi, Eslam B. Elkaeed, Mohammed A. S. Abourehab, Hatem A. Abdel-Aziz, Ahmed M. El Kerdawy

    Published 2022
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  10. 10
    Enaminone-based carboxylic acids as novel non-classical carbonic anhydrases inhibitors: design, synthesis and in vitro biological assessment

    Enaminone-based carboxylic acids as novel non-classical carbonic anhydrases inhibitors: design, synthesis and in vitro biological assessment by Mahmoud F. Abo-Ashour, Hadia Almahli, Alessandro Bonardia, Amira Khalil, Tarfah Al-Warhi, Sara T. Al-Rashood, Hatem A. Abdel-Aziz, Alessio Nocentini, Claudiu T. Supuran, Wagdy M. Eldehna

    Published 2022
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  11. 11
    Design and synthesis of benzothiazole-based SLC-0111 analogues as new inhibitors for the cancer-associated carbonic anhydrase isoforms IX and XII

    Design and synthesis of benzothiazole-based SLC-0111 analogues as new inhibitors for the cancer-associated carbonic anhydrase isoforms IX and XII by Tarfah Al-Warhi, Mostafa M. Elbadawi, Alessandro Bonardi, Alessio Nocentini, Ahmed A. Al-Karmalawy, Nada Aljaeed, Ohoud J. Alotaibi, Hatem A. Abdel-Aziz, Claudiu T. Supuran, Wagdy M. Eldehna

    Published 2022
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  12. 12
    Cancer stem cells CD133 inhibition and cytotoxicity of certain 3-phenylthiazolo[3,2-a]benzimidazoles: design, direct synthesis, crystal study and in vitro biological evaluation

    Cancer stem cells CD133 inhibition and cytotoxicity of certain 3-phenylthiazolo[3,2-a]benzimidazoles: design, direct synthesis, crystal study and in vitro biological evaluation by Ghada H. Al-Ansary, Wagdy M. Eldehna, Hazem A. Ghabbour, Sara T. A. Al-Rashood, Khalid A. Al-Rashood, Radwa A. Eladwy, Abdullah Al-Dhfyan, Maha M. Kabil, Hatem A. Abdel-Aziz

    Published 2017
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  13. 13
    Development of novel isatin-nicotinohydrazide hybrids with potent activity against susceptible/resistant Mycobacterium tuberculosis and bronchitis causing-bacteria

    Development of novel isatin-nicotinohydrazide hybrids with potent activity against susceptible/resistant Mycobacterium tuberculosis and bronchitis causing-bacteria by Zainab M. Elsayed, Wagdy M. Eldehna, Marwa M. Abdel-Aziz, Mahmoud A. El Hassab, Eslam B. Elkaeed, Tarfah Al-Warhi, Hatem A. Abdel-Aziz, Sahar M. Abou-Seri, Eman R. Mohammed

    Published 2021
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  14. 14
    Development of novel benzofuran-isatin conjugates as potential antiproliferative agents with apoptosis inducing mechanism in Colon cancer

    Development of novel benzofuran-isatin conjugates as potential antiproliferative agents with apoptosis inducing mechanism in Colon cancer by Wagdy M. Eldehna, Rofaida Salem, Zainab M. Elsayed, Tarfah Al-Warhi, Hamada R. Knany, Rezk R. Ayyad, Thamer Bin Traiki, Maha-Hamadien Abdulla, Rehan Ahmad, Hatem A. Abdel-Aziz, Radwan El-Haggar

    Published 2021
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  15. 15
    Development of 2-oxindolin-3-ylidene-indole-3-carbohydrazide derivatives as novel apoptotic and anti-proliferative agents towards colorectal cancer cells

    Development of 2-oxindolin-3-ylidene-indole-3-carbohydrazide derivatives as novel apoptotic and anti-proliferative agents towards colorectal cancer cells by Wagdy M. Eldehna, Mahmoud F. Abo-Ashour, Tarfah Al-Warhi, Sara T. Al-Rashood, Amal Alharbi, Rezk R. Ayyad, Khayal Al-Khayal, Maha Abdulla, Hatem A. Abdel-Aziz, Rehan Ahmad, Radwan El-Haggar

    Published 2021
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  16. 16
    Novel [(N-alkyl-3-indolylmethylene)hydrazono]oxindoles arrest cell cycle and induce cell apoptosis by inhibiting CDK2 and Bcl-2: synthesis, biological evaluation and in silico studies

    Novel [(N-alkyl-3-indolylmethylene)hydrazono]oxindoles arrest cell cycle and induce cell apoptosis by inhibiting CDK2 and Bcl-2: synthesis, biological evaluation and in silico stud... by Tarfah Al-Warhi, Mahmoud F. Abo-Ashour, Hadia Almahli, Ohoud J. Alotaibi, Mohammad M. Al-Sanea, Ghada H. Al-Ansary, Hanaa Y. Ahmed, Mahmoud M. Elaasser, Wagdy M. Eldehna, Hatem A. Abdel-Aziz

    Published 2020
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  17. 17
    Discovery of 2,4-thiazolidinedione-tethered coumarins as novel selective inhibitors for carbonic anhydrase IX and XII isoforms

    Discovery of 2,4-thiazolidinedione-tethered coumarins as novel selective inhibitors for carbonic anhydrase IX and XII isoforms by Wagdy M. Eldehna, Mohammed S. Taghour, Tarfah Al-Warhi, Alessio Nocentini, Mostafa M. Elbadawi, Hazem A. Mahdy, Mohamed A. Abdelrahman, Ohoud J. Alotaibi, Nada Aljaeed, Diaaeldin M. Elimam, Kamyar Afarinkia, Hatem A. Abdel-Aziz, Claudiu T. Supuran

    Published 2022
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  18. 18
    WRH-2412 alleviates the progression of hepatocellular carcinoma through regulation of TGF-β/β-catenin/α-SMA pathway

    WRH-2412 alleviates the progression of hepatocellular carcinoma through regulation of TGF-β/β-catenin/α-SMA pathway by Mohammed A. F. Elewa, Wagdy M. Eldehna, Ahmed M. E. Hamdan, Samraa H. Abd El-kawi, Asmaa M. El-Kalaawy, Taghreed A. Majrashi, Reham F. Barghash, Hatem A. Abdel-Aziz, Khalid S. Hashem, Mohammed M. H. Al-Gayyar

    Published 2023
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  19. 19
    Discovery of novel thiazolyl-pyrazolines as dual EGFR and VEGFR-2 inhibitors endowed with in vitro antitumor activity towards non-small lung cancer

    Discovery of novel thiazolyl-pyrazolines as dual EGFR and VEGFR-2 inhibitors endowed with in vitro antitumor activity towards non-small lung cancer by Esraa A. Abdelsalam, Amer Ali Abd El-Hafeez, Wagdy M. Eldehna, Mahmoud A. El Hassab, Hala Mohamed M. Marzouk, Mahmoud M. Elaasser, Nageh A. Abou Taleb, Kamilia M. Amin, Hatem A. Abdel-Aziz, Pradipta Ghosh, Sherif F. Hammad

    Published 2022
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