Increased Nucleosomes and Neutrophil Activation Link to Disease Progression in Patients with Scrub Typhus but Not Murine Typhus in Laos. by Daniel H Paris, Femke Stephan, Ingrid Bulder, Diana Wouters, Tom van der Poll, Paul N Newton, Nicholas P J Day, Sacha Zeerleder

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A thrombomodulin mutation that impairs active protein C generation is detrimental in severe pneumonia-derived gram-negative sepsis (melioidosis). by Liesbeth M Kager, W Joost Wiersinga, Joris J T H Roelofs, Onno J de Boer, Hartmut Weiler, Cornelis van 't Veer, Tom van der Poll

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Expression and Function of Granzymes A and B in Escherichia coli Peritonitis and Sepsis by M. Isabel García-Laorden, Ingrid Stroo, Sanne Terpstra, Sandrine Florquin, Jan Paul Medema, Cornelis van´t Veer, Alex F. de Vos, Tom van der Poll

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Toll-Like Receptor 9 Enhances Bacterial Clearance and Limits Lung Consolidation in Murine Pneumonia Caused by Methicillin-Resistant Staphylococcus aureus by Anne Jan van der Meer, Achmed Achouiti, Arie van der Ende, Aicha Ait Soussan, Sandrine Florquin, Alex de Vos, Sacha S Zeerleder, Tom van der Poll

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Btk inhibitor ibrutinib reduces inflammatory myeloid cell responses in the lung during murine pneumococcal pneumonia by Alexander P. de Porto, Zhe Liu, Regina de Beer, Sandrine Florquin, Onno J. de Boer, Rudi W. Hendriks, Tom van der Poll, Alex F. de Vos

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Hypoxia-Inducible Factor-1α in Macrophages, but Not in Neutrophils, Is Important for Host Defense during Klebsiella pneumoniae-Induced Pneumosepsis by Natasja A. Otto, Liza Pereverzeva, Valentine Leopold, Ivan Ramirez-Moral, Joris J. T. H. Roelofs, Jeroen W. J. van Heijst, Alex F. de Vos, Tom van der Poll

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Osteopontin impairs host defense during established gram-negative sepsis caused by Burkholderia pseudomallei (melioidosis). by Gerritje J W van der Windt, W Joost Wiersinga, Catharina W Wieland, Ivo C S I Tjia, Nicholas P Day, Sharon J Peacock, Sandrine Florquin, Tom van der Poll

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Soluble ST2 levels are associated with bleeding in patients with severe Leptospirosis. by Jiri F P Wagenaar, M Hussein Gasem, Marga G A Goris, Mariska Leeflang, Rudy A Hartskeerl, Tom van der Poll, Cornelis van 't Veer, Eric C M van Gorp

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Expression of intra- and extracellular granzymes in patients with typhoid fever. by Hanna K de Jong, Maria Isabel Garcia-Laorden, Arie J Hoogendijk, Christopher M Parry, Rapeephan R Maude, Arjen M Dondorp, Mohammed Abul Faiz, Tom van der Poll, Willem Joost Wiersinga

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Increased Von Willebrand factor, decreased ADAMTS13 and thrombocytopenia in melioidosis. by Emma Birnie, Gavin C K W Koh, Ester C Löwenberg, Joost C M Meijers, Rapeephan R Maude, Nicholas P J Day, Sharon J Peacock, Tom van der Poll, W Joost Wiersinga

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Triggering Receptor Expressed on Myeloid Cells (TREM)-2 Impairs Host Defense in Experimental Melioidosis. by Tassili A F Weehuizen, Tijmen J Hommes, Jacqueline M Lankelma, Hanna K de Jong, Joris J T H Roelofs, Alex F de Vos, Marco Colonna, Tom van der Poll, W Joost Wiersinga

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Correction: Increased Von Willebrand factor, decreased ADAMTS13 and thrombocytopenia in melioidosis. by Emma Birnie, Gavin C K W Koh, Ester C Löwenberg, Joost C M Meijers, Rapeephan R Maude, Nicholas P J Day, Sharon J Peacock, Tom van der Poll, W Joost Wiersinga

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Expression and function of macrophage migration inhibitory factor (MIF) in melioidosis. by W Joost Wiersinga, Thierry Calandra, Liesbeth M Kager, Gerritje J W van der Windt, Thierry Roger, Didier le Roy, Sandrine Florquin, Sharon J Peacock, Fred C G J Sweep, Tom van der Poll

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Bruton's Tyrosine Kinase in Neutrophils Is Crucial for Host Defense against Klebsiella pneumoniae by Zhe Liu, Alexander P.N.A. De Porto, Regina De Beer, Joris J.T.H. Roelofs, Onno J. De Boer, Sandrine Florquin, Cornelis Van't Veer, Rudi W. Hendriks, Tom Van der Poll, Alex F. De Vos

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The gut microbiota as a modulator of innate immunity during melioidosis. by Jacqueline M Lankelma, Emma Birnie, Tassili A F Weehuizen, Brendon P Scicluna, Clara Belzer, Riekelt H Houtkooper, Joris J T H Roelofs, Alex F de Vos, Tom van der Poll, Andries E Budding, W Joost Wiersinga

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Glyburide reduces bacterial dissemination in a mouse model of melioidosis. by Gavin C K W Koh, Tassili A Weehuizen, Katrin Breitbach, Kathrin Krause, Hanna K de Jong, Liesbeth M Kager, Arjan J Hoogendijk, Antje Bast, Sharon J Peacock, Tom van der Poll, Ivo Steinmetz, W Joost Wiersinga

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Overexpression of the endothelial protein C receptor is detrimental during pneumonia-derived gram-negative sepsis (Melioidosis). by Liesbeth M Kager, Marcel Schouten, W Joost Wiersinga, J Daan de Boer, Lionel C W Lattenist, Joris J T H Roelofs, Joost C M Meijers, Marcel Levi, Arjen M Dondorp, Charles T Esmon, Cornelis van 't Veer, Tom van der Poll

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Expression and function of S100A8/A9 (calprotectin) in human typhoid fever and the murine Salmonella model. by Hanna K De Jong, Ahmed Achouiti, Gavin C K W Koh, Christopher M Parry, Stephen Baker, Mohammed Abul Faiz, Jaap T van Dissel, Albert M Vollaard, Ester M M van Leeuwen, Joris J T H Roelofs, Alex F de Vos, Johannes Roth, Tom van der Poll, Thomas Vogl, Willem Joost Wiersinga

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